chordoma


Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.

chordoma

a rare congenital tumor of the brain.
See also: Cancer
Mentioned in ?
References in periodicals archive ?
Bavarian Nordic A/S (CPH:BAVA) (OTC: BVNRY), a biotechnology company focused on the development of innovative therapies against cancer and infectious diseases, announced on Wednesday the confirmation by the Data and Safety Monitoring Board (DSMB) of a partial response in one of the first chordoma patients recruited and treated with the combination of BN-Brachyury and radiation treatment at the first evaluation timepoint.
Aaron was told by doctors here his only option was palliative care after he was diagnosed with a chordoma.
(3) Masses originating from the clivus include bony metastases, chordomas, chondrosarcomas and plasmacytomas.
Charged particle irradiation of chordoma and chondrosarcoma of the base of skull and cervical spine: the Lawrence Berkeley Laboratory experience.
These case studies featured rare tumors including central neurocytoma, cervical chordoma, germinoma, spinal epidural lipomatosis, glomus jugulare, neurofibromatosis type 2, and craniopharyngioma.
The partial clinical hold was initiated following a safety report, submitted by Epizyme to the FDA and other regulatory authorities, regarding a patient with advanced poorly differentiated chordoma in the company's Phase 1 pediatric study who developed a secondary T-cell lymphoma.
(9) Individual tumor cells are often round to oval with scant or moderate eosinophillic cytoplasm and pleomorphic nuclei with rhabdoid and epitheloid cells scattered at periphery.9 ESMC expresses neuroendocrine differentiation with strong immunopositivity for vimentin and synaptophysin (7) and weak or focal positivity for EMA and S-100.7 Myxoid matrix with lobulated neoplastic cells is also seen in chordoma, parachordoma, chordoid meningiomas, and myxopapillary ependymoma.
The most common histologic types included chondrosarcoma (42%), osteosarcoma (30%), Ewing's sarcoma (10%), and chordoma (10%).
Among the 30 lesions, there are 12 metastatic neoplasms (in 11 subjects), 6 meningiomas, 3 cavernous hemangiomas, 3 germ cell tumors, 2 hemangiopericytomas, 2 adenoid cystic carcinomas, 1 chordoma, and 1 hypophysoma.
Twenty-five cases of conventional OSA and 25 cases of OPBT (consists of angiosarcoma, chondrosarcoma, chordoma, Ewing's Sarcoma, malignant giant cell tumour, low grade fibromyxoid sarcoma, and plasmacytoma) were included in this study.
The pelvic computed tomography (CT) revealed a 9x7.5x9 cm bulky mass in the sacrum with locally increased soft tissue density, causing extensive lytic lesions of the sacred vertebrae and extending to the left iliac bone, suggestive of chordoma. The patient underwent total sacrectomy with partial excision and reconstruction of the left iliac bone.