Clearside Biomedical announced its entry into a worldwide licensing agreement with Aura Biosciences for the use of Clearside's Suprachoroidal Space Microinjectorto deliver Aura's proprietary drug candidates into the SCS for the potential treatment of certain ocular cancers, including choroidal
- US-based Aura Biosciences, a specialist in the development of novel targeted therapies in ocular oncology, will present interim clinical data from its Phase 1b/2 clinical trial evaluating the safety and efficacy of light-activated AU-011, the company's lead product candidate for the primary treatment of primary choroidal
melanoma, in an oral presentation at the International Society of Ocular Oncology 2019 annual meeting being held next week, the company said.
Patients with visual loss associated with other retinal (retinal vascular pathologies) or corneal pathologies and patients with choroidal
neovascularization not related to AMD were excluded from the study.
A 56-year-old man with choroidal
melanoma in the left eye had no underlying disease or perioperative abnormality.
thickness (CT) can increase or decrease in response to vasodilatation and vasoconstriction in its vascular structures.
A study published in the American Journal of Physiology found that astronauts with higher weight, waist and chest circumference measurements were more likely to develop disc oedema or choroidal
Changes in central macular thickness and subfoveal choroidal
thickness before and after drug injection have been of interest since the invention of optical coherence tomography in recent years (9,10).
Microvascular changes caused by obesity may result in damage to the optic nerve, retinal nerve fiber layer (RNFL) and choroidal
regions, and damage can be revealed in the early period with optic coherence tomography (OCT).
The areas they cover are age-related macular degenerations, macular diseases, diabetic retinopathy, retinal vascular disease, retinal degenerations and dystrophies, retinal and choroidal
tumors, congenital and pediatric retinal diseases, traumatic and toxic retinopathies, and peripheral retinal disease.
The other four patients had unilateral involvement: retinal vasculitis in the right eye (one case); choroidal
nodules in the right eye (two cases); and choroidal
nodules in the left eye (one case).
MONDAY, April 23, 2018 (HealthDay News) -- The choroidal
thickness changes in patients with untreated diabetes mellitus over time, according to a study published online April 14 in Clinical & Experimental Ophthalmology.
Several high-risk factors documented to be associated with extraocular recurrence have been identified upon Histopathological (HP) examination of enucleated eyes, which include invasion of post-laminar optic nerve, trans-scleral migration, choroidal
invasion and anterior chamber seeding.