chromatolysis


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Related to chromatolysis: calciphylaxis, wallerian degeneration, neuronophagia, Monckeberg arteriosclerosis, Astrocytes

chro·ma·tol·y·sis

 (krō′mə-tŏl′ĭ-sĭs)
n.
The dissolution or disintegration of chromophil material, such as chromatin, within a cell.

chro·mat′o·lyt′ic (-măt′l-ĭt′ĭk) adj.

chromatolysis

(ˌkrəʊməˈtɒlɪsɪs)
n
(Biology) cytology the dissolution of stained material, such as chromatin in injured cells

chromatolysis

the breakdown of the protoplasm that contains the genes in the cell nucleus.
See also: Cells
References in periodicals archive ?
Histologic examination of the brain revealed microspongiosis, edema, gliosis, and neuronal chromatolysis of surrounding periventricular tissue.
This observation may suggest that following chromatolysis and degeneration of the nucleus in both GCs and oocytes, intensive deficiency in proteins and in the metabolism of carbohydrates, as an essential source of energy, will occur.
In a postmortem study of nine patients with RA and myelopathy, Henderson and coworkers (31) noted that the cord pathology occurred mostly in the dorsal white matter of the spinal cord and was characterized by axonal degeneration, central chromatolysis, and axonal retraction.
Vestibulocochlear Wallerian-like degeneration and retinal ganglion cell chromatolysis were also seen in dogs treated for 14 weeks at 180 mg/kg/day, a dose which resulted in a mean plasma drug level (Cmax) similar to that seen with the 60 mg/kg/day dose.