(redirected from chromocenter)
Also found in: Medical, Encyclopedia.


An irregular aggregation of chromatin in the nucleus of a cell not undergoing mitosis.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


1. (Biology) any of the dense aggregates of chromatin in the nucleus of a cell
2. (Biology) the nucleus of a cell
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈkær i əˌsoʊm)

any of several masses of chromatin in the reticulum of a cell nucleus.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
maculata (Figure 1A) showed a heterochromatic chromocenter formed by the sex chromosomes (arrow) and small heterochromatic blocks dispersed in nucleus; T.
maculata, the chromocenter is formed by sex chromosomes, different of the species the Brasiliensis subcomplex which has the chromocenter form by sex chromosomes plus one pair of autosomes.
After injection with 0.7 and 1.7 mL/kg dose of iron oxide nanoparticles, there were noticed splenic red pulp with discreet nuclear contour irregularities, discreet anisochromia with focal chromocenter formation, and rare nucleoli.
Hepatocytes with discreet anisokaryosis, formation of chromocenters and nucleoli, and focal intrahepatocyte cholestasis (HE, 600x) were found in the liver of both the IO-NPs (0.7 mL/kg) treated and control groups (Figure 5(a)) with no significant difference between them.
Specifically, genetic equilibrium for sex chromosomes and equilibrium for the IS-1 autosomal polymorphism in both 2009 and 2010 and lack of differences in pairing and chromocenter morphologies all argue against a hybridization event.
On the cytological level, during interphase, the chromosomes in animals, such as flies, are all joined together in a common heterochromatic region, referred to as the chromocenter. (17) In some situations, there is even a physical continuity between chromosomes and membrane.
We additionally found that in approximately 90% of the cell nuclei at the cortex periphery, the Cajal bodies (CBs) were located away from clusters of centromeric heterochromatin called chromocenters (Figure 1(c)).
These nuclei are very large, with absence of chromosome threads and with diffuse nucleoplasm, except for a number of prominent chromocenters thought to be the pericentromeric heterochromatin.
Prominent chromocenters. Category IV Suspicious for Single cells and groups of cells malignancy with nuclear features suspicious for cancer.