Around 0.3 million people die annually because of burn wounds around the globe with nosocomial infections contributing in 50% of these deaths.1 Gram negative, non-spore forming organism, Pseudomonas aeruginosa is responsible for 10-20% hospital acquired infections and causes 40-75% mortality in burn patients.2 Broad spectrum antimicrobial drugs, fluoroquinolones (FQn), are commonly suggested against pseudomonal infections.3 Misuse of FQn has led to an increase in bacterial resistance due to
chromosomal mutation in DNA gyrase (gyr A and gyr B genes) and topoisomerase IV or changes in expression of genes controlling transport of FQns.4 Another important acquired mechanism of FQn resistance is Qnr genes.
Caption: GENETIC ABNORMALITIES: Deletion, duplication, inversion and translocation are the four types of
chromosomal mutation. If a significant amount of genetic information is lost, the mutation is likely to have life-threatening consequences.
n number of jobs m number of machines [p.sub.ij] processing time of job i on machine j [p.sub.m] probability of mutation [P.sub.to] probability for Roulette wheel selection [p.sub.sc] probability for sub chromosomal crossover [P.sub.sm] probability for sub
chromosomal mutation P(k) population at kth generation X* , X** best and second best chromosomes R real random number is 0 and 1 Ng maximum generation 3.
Unfortunately, Filipinos do not possess the
chromosomal mutation nor the milk consuming culture that will enable them to continuously produce lactase.
Researchers in the Keck School of Medicine of the University of Southern California (USC), together with scientists in Beijing, China, have discovered a
chromosomal mutation responsible for a very rare condition in which people grow excess hair all over their bodies.
It is thought that Dubowitz syndrome is an inherited genetic condition or
chromosomal mutation, but no formal test exists beyond the physical examination.
These chemicals have been linked to a variety of health complications, including nervous and immune system dysfunction and
chromosomal mutation. On average, CSE found that PepsiCo brands contained 36 times the pesticides permitted under EEC standards, and Coca-Cola brands contained 30 times the amount allowed.
To my knowledge, there is no indication that couples who undergo PGD because they are at high risk for a Mendelian disorder or
chromosomal mutation consistently or routinely choose embryos of one sex over another.
Because most ROS are short-lived and can only diffuse short distances in cells, it is still not clear how these radicals reach the nucleus to cause gene and
chromosomal mutation (54,55).
Increased
chromosomal mutation rate after hybridization between two subspecies of grasshoppers.
Washington, June 4 (ANI): An Indian-origin researcher and her team have discovered a
chromosomal mutation responsible for a very rare condition in which people grow excess hair all over their bodies.
In most cases, expression of the components of the efflux system is regulated, and resistance occurs by
chromosomal mutation that causes coordinated increased expression of pump components.
