Basidiomycetous fungal Inonotus tropicalis sacral osteomyelitis in X-linked chronic granulomatous disease
Patients who were treated by Ege University, Faculty of Medicine, Division of Pediatric Immunology for severe combined and combined immune deficiency (n=45), IL-12/IFN-Y receptor disorder (n=7), NEMO disorder (n=1), and chronic granulomatous disease
(n=21) were evaluated retrospectively in terms of mycobacterial infections.
And in her personal history, there were not found any data related to recurrent infectious processes, either in childhood or present, which does not lead to suspicion of diseases with primary immunodeficiencies, in which recurrent infections would be expected as in the case of recurrent pneumonia, lung, spleen and liver abscesses, cervical, axillary and inguinal lymphadenitis, or bone and skin infections, as in the case of chronic granulomatous disease
Additionally, we evaluated infections such as tuberculosis, histoplasmosis, brucellosis, schistosomiasis, hydatid cyst, cytomegalovirus, toxoplasmosis, Pneumocystis carinii infection, chronic amebic or pyogenic abscess, and chronic granulomatous disease
Leprosy is a chronic granulomatous disease
primarily affecting the skin and peripheral nervous system.
The following conditions/diseases may cause the immune system to be compromised and/or suppressed: Transplantation or Immunosuppressant patients, Chemotherapy/Cancer patients, Overwhelming infection, Poor nutrition, AIDS/HIV, Primary Immune Deficiency, Selective IgA Deficiency, Common Variable Immunodeficiency, X-Linked Agammaglobulinemia, Chronic Granulomatous Disease
, Hyper-IgM Syndrome, Severe Combined Immunodeficiency Disease (SCID), and some newborns diabetes.
In this article, we present a healthy patient with pain in the cranium diagnosed with chronic granulomatous disease
and aspergillus osteomy-elits.
Initial evaluation for suspected CID should include a complete blood count, quantitative immunoglobulins, mitogen stimulation assay' tetanus titer, T- and B-cell flow cytometry' and nitroblue tetrazolium or chronic granulomatous disease
flow assay, said Dr.
Fas and FasL expression in leukocytes from Chronic Granulomatous Disease
It is indicated for the treatment of two life-threatening congenital diseases: chronic granulomatous disease
and severe, malignant osteopetrosis.
Initial evaluation for suspected CID should include a complete blood count, quantitative immunoglobulins, mitogen stimulation assay, tetanus titer, T- and B-cell flow cytometry, and nitroblue tetrazolium or chronic granulomatous disease
flow assay, said Dr.
Chronic granulomatous disease
is a relatively uncommon immunodeficiency disorder inherited either in an X-linked or autosomal recessive manner.