It added that summertime arrangements are estimated to generate positive effects linked to more outdoor leisure activities but on the other hand, chronobiologic
research findings suggest that the effect on the human biorhythm may be more severe than previously thought.
This short review article focuses on two main issues in PCOS-MS phenotype development: (a) the impact of androgen excess on WAT function and (b) a possible adjuvant melatonin therapy to improve the chronobiologic
profile in PCOS individuals.
Frederickson, "The use of bright light in the treatment of chronobiologic
sleep and mood disorders: the phase-response curve," Psychopharmacology Bulletin, vol.
We can refer again to the double face of Mel, as a chronobiologic
hormone and as a highly efficient antioxidant and free radical scavenger.
reference values in clinical chemistry.
Not only is saliva testing more accurate, inasmuch as it measures only the active free hormone, but it also allows chronobiologic
testing, which is not feasible with serum testing with its attendant venipunctures.
Studies by our group (10) and others (11) have shown that overattention to mood variation without considering associated cognitive, speech-language, chronobiologic
, and motor signs of mania /hypomania accounts for substantial overdiagnosis of BD in patients with non-specific mood disturbances, particularly in those with active substance abuse or borderline personality disorder (BPD).
With respect to circadian dysregulation, research suggests that chronobiologic
abnormalities, in the form of phase shifts of the core-body temperature rhythm, are related to sleep initiation or maintenance problems (12).