. By discovering links like these, chronobiologists are opening new avenues to treating diseases.
Goel, associate professor in the division of sleep and chronobiology
in the department of psychiatry at the University of Pennsylvania, Philadelphia, and colleagues enrolled 12 healthy adults to participate in a randomized cross-over study in free-living conditions.
Commenting on the paper, Malcolm von Schantz, a professor of Chronobiology
at the University of Surrey in Britain said: "What is novel with this paper is that it is a longitudinal study comparing the weight of the same individuals at baseline and more than five years later."
It also has implications in chronobiology
based exercise therapy for patients with metabolic disorders.
"While it's a common notion that sleep and healing are tightly related, our study directly links sleep to the immune system and provides a potential explanation for how sleep increases during sickness," said senior author Amita Sehgal, PhD, a professor of Neuroscience and director of Penn's Chronobiology
and Biometrics Research groups at Columbia University's Psychiatric, 2003.
Prima-Temp combines chronobiology
and advanced intelligence machine learning, utilising circadian rhythm patterns to track and alert as to a variety of important health parameters.
Led by Surrey university's Reader in Chronobiology
and Integrative Physiology, Dr Jonathan Johnston, the research involved a number of participants over the course of a 10-week study.
The published accounts of de Mairan's work stimulated further research in the field of chronobiology
According to co-author Kenneth Wright, the director of the Sleep and Chronobiology
Laboratory and professor in the Department of Integrative Physiology, "this tells us that when we experience things like jet lag or a couple of nights of shift work, we very rapidly alter our normal physiology in a way that if sustained can be detrimental to our health." The study is the first of its kind to examine how protein levels in human blood, also known as plasma proteome, vary over a 24-hour period and how altered sleep and meal timing affects them.
Dr Jonathan Johnston, reader in chronobiology
and integrative physiology at the University of Surrey, said although studies suggest our bodies are less good at processing food in the evening it was not yet understood why this is.