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 (kī′mō-pə-pā′ĭn, -pī′ĭn)
A proteolytic enzyme that is obtained from unripe papaya fruits and is similar to papain. It was formerly used in the United States to treat herniated intervertebral disks.


(ˌkaɪ moʊ pəˈpeɪ ɪn, -ˈpaɪ ɪn)

an enzyme of the papaya that is capable of breaking down protein: used to dissolve cartilage in the treatment of herniated disks.
References in periodicals archive ?
Chemonucleolysis versus open discectomy: the case against chymopapain.
15] Proteolytic enzymes like papain and chymopapain may help increase platelet count, and alkaloid fraction (carpaine) has shown to be responsible for the anti-thrombocytopenic activity.
Pawpaw is a rich source of enzymes known as papain and chymopapain which have antiviral, antibacterial and antifungal properties [15].
1,2 The nutritional content of fruit is composed of vitamin A, vitamin C, Calcium, chymopapain and papain etc.
What does it do: The sap of the fruit contains two enzymes, Papain and Chymopapain, the minerals iron, potassium, phosphorus and calcium; vitamins A, B complex, and C.
In 1941, Jansen and Balls first isolated chymopapain from crude papain derived from the papaya fruit.
Five-year results from chemonucleolysis with chymopapain or collagenase: A prospective randomized study.
Papaya proteases consists of four related molecular weight cysteine-proteases, which donate 6989% of total protein, up to 10 % of papain, 1426 % of caricain, 2328 % of glycyl-endopeptidase and 2630 % of chymopapain.
Papaya leaves contain active compounds papain chymopapain alkaloids flavonoids flavonaols benzylglucosinolate and tannins.
Along with a hefty amount of fibre, papayas contain two compounds, chymopapain and papain, that help the body produce enzymes necessary for breaking down protein and harmful waste, according to researchers at Cornell University.
Previous reports have indicated that papaya contain a-tocopherol (Ching & Mohamed, 2001), lycopene (van Breemen & Pajkovic, 2008), benzylisothiocyanate (Basu & Haldar, 2008), proteolytic enzymes such as papain and chymopapain (Seigler et al.