Additional information is available about ciguatoxin
testing of implicated fish from the Gulf Coast Seafood Laboratory of the Food and Drug Administration (FDA) in Dauphin Island, Alabama, telephone (334) 694-4480, or the University of Hawaii, Honolulu, telephone (808) 956-8682.
Laboratory diagnostics of brevetoxin and ciguatoxin
intoxication in humans: case reports and sampling consideration In: Proceedings of the 5th Indo-Pac Fish Conference (Seret B, Syre J-Y, eds), 3-8 November 1997, Noumea, New Caledonia.
The diagnosis is supported by detection of ciguatoxin
in the implicated fish.
More than 80% of the seafood-related outbreaks were caused by scombrotoxin or ciguatoxin
, heat-resistant toxins found in warmwater species of fish.
Chemical agents caused 45 outbreaks (264 cases): ciguatoxin
caused 13 outbreaks (43 cases), and scombrotoxin caused 13 outbreaks (27 cases).
The egg microinjection method had already been used to characterize the adverse effects of known bioaccumulants such as ciguatoxin
(a related polyether toxin also produced by a dinoflagellate) and the pesticide DDT in medaka fish.
This method has previously been used to characterize the adverse effects of ciguatoxin
and chemical contaminants such as DDT (19,20).
Production of ciguatoxin
and maitotoxin by strains of Gambierdiscus australes, G.
Transcriptomic signatures in whole blood of patients who acquire a chronic inflammatory response syndrome (CIRS) following an exposure to the marine toxin ciguatoxin
. BMC Med Genomics.
Experts aren't completely sure how Mannitol treats the illness, but they agree that it somehow interrupts the swelling of nerve cells caused by the ciguatoxin
foertherianum and one of its isolated compounds rosmarinic acid were assessed for its effects against a pacific ciguatoxin
(P-CTX-1B) in the neuroblastoma cytotoxicity assay and the receptor-binding assay.