cisplatin


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cis·plat·in

 (sĭs-plăt′n, -plā′tn)
n.
A platinum-containing chemotherapeutic drug, Cl2H6N2Pt, used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer. Also called cisplatinum.

[Short for cisplatinum.]

cisplatin

(sɪsˈplætɪn)
n
(Pharmacology) a cytotoxic drug that acts by preventing DNA replication and hence cell division, used in the treatment of tumours, esp of the ovary and testis
[C20: from cis- + platin(um)]
Translations

cisplatin

n cisplatino
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References in periodicals archive ?
Locomotion and rearing activity decreased after cisplatin administration with and without SAHA pretreatment.
Schornagel et al., "Randomized phase III trial of high-dose-intensity methotrexate, vinblastine, doxorubicin, and cisplatin (MVAC) chemotherapy and recombinant human granulocyte colony-stimulating factor versus classic MVAC in advanced urothelial tract tumors: european organization for research and treatment of cancer protocol no.
Lippard, "Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate," Proceedings of the National Academy of Sciences, vol.
Randomized phase III trial of concurebt accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma:RTOG 0522.
Long-term follow-up of patients with good-risk germ cell tumors treated with etoposide and cisplatin. J Clin Oncol.
Taurine protects cisplatin induced cardiotoxicity by modulating inflammatory and endoplasmic reticulum stress responses.
Cisplatin is an antineoplastic agent often used in malign neoplasms such as those in gastrointestinal systems, urinary system, and head and neck.
Cisplatin-resistant sublines (SW480) were selected by double subcloning using the limiting dilution method from cultures continuously exposed to increasing concentrations of cisplatin (14).
Cisplatin plus ifosfamide-containing regimens form the backbone of salvage CDCT, with studies testing a variety of third drugs to add to this combination.
MPM patients are negatively affected by mostly insufficient current treatment modalities consisting of platinumcontaining regimes using cisplatin [6] or carboplatin [7-10] as first choice.
In the Phase Ib study of Acelarin combined with cisplatin, we observed an approximate doubling of the response rate expected with the standard of care, gemcitabine plus cisplatin, with several patients achieving significant reductions in their tumor volume as well as further tumor shrinkage over time.
ENPNewswire-July 29, 2019--Hikma launches Cisplatin Injection