Commonly used chemotherapy agents include
cisplatinum, epirubicin, 5-fluorouracil, and recombinant interferon [alpha]-2b; however, FLC does not respond to chemotherapy as well as classical HCC.
In 1964, Rosenberg [9] discovered that platinum complexes have the ability to inhibit cell division, and
cisplatinum was later confirmed to be the effective chemical.
The other group was treated with
cisplatinum (30[micro]M) for 6 h before cell lysis.
Kiyuna et al., "Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and
cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: decoy, trap and kill chemotherapy moves toward the clinic," Cell Cycle, vol.
Muijs et al., "A comparison of carboplatin and paclitaxel with
cisplatinum and 5-fluorouracil in definitive chemoradiation in esophageal cancer patients," Annals of Oncology, vol.
Neoadjuvant
cisplatinum based combination chemotherapy in patients with invasive bladder cancer: a combined analysis of two Nordic studies; Nordic Urothelial Cancer Group.
Nabilone and metoclopramide in the treatment of nausea and vomiting due to
cisplatinum: a double blind study.
Concurrent
cisplatinum and radiation with or without surgery for advanced head and neck cancer.
One can see the presence of both IR bands of copolymer and
cisplatinum at the vicinity of 782, 1290, 2848, and 3271 [cm.sup.-1] of resulting spectrum.
Cvitkovic, "
Cisplatinum ototoxicity," Clinical Toxicology, vol.
Mozzon et al., "
Cisplatinum and transplatinum complexes with benzyliminoether ligands; synthesis, characterization, structure-activity relationships, and in vitro and in vivo antitumor efficacy," Journal of Medicinal Chemistry, vol.
Xu, "Preparation of two kinds of superparamagnetic carriers-supported
cisplatinum complexes and the comparison of their characteristics," Chinese Science Bulletin, vol.