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cleave 1

v. cleft (klĕft) or cleaved or clove (klōv), cleft or cleaved or clo·ven (klō′vən), cleav·ing, cleaves
1. To split with a sharp instrument. See Synonyms at tear1.
2. To make or accomplish by or as if by cutting: cleave a path through the ice.
3. To pierce or penetrate: The wings cleaved the foggy air.
4. Chemistry To split (a complex molecule) into simpler molecules.
1. To split or be capable or splitting, especially along a natural line of division: Certain brittle woods cleave easily.
2. To penetrate or pass through something, such as water or air.

[Middle English cleven, from Old English clēofan; see gleubh- in Indo-European roots.]

cleav′a·ble adj.

cleave 2

intr.v. cleaved, cleav·ing, cleaves
1. To adhere, cling, or stick fast.
2. To be faithful: cleave to one's principles.

[Middle English cleven, from Old English cleofian.]


(ˈkli və bəl)

capable of being split.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.cleavable - capable of being cleaved
divisible - capable of being or liable to be divided or separated; "even numbers are divisible by two"; "the Americans fought a bloody war to prove that their nation is not divisible"
References in periodicals archive ?
The unique design of the selectively cleavable linker connecting the antibody to the duocarmycin drug leads to high stability in circulation, and induces efficient release of the cytotoxin in the tumor.
RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers.
developed MORAb-202, which combines anticancer agent farletuzumab, an IgG1 monoclonal antibody that binds to the folate receptor alpha, and Eisai's in-house developed anticancer agent eribulin using an enzyme cleavable linker.
This vector permits the genes of interest to be fused to the thioredoxin fusion protein, trxA, for high levels of expression with good solubility and it also contains cleavable His-tag sequences for detection and purification.
PA polypeptide chain has the cleavable N-terminal leader peptide targeting the protein to the secretion via Sec pathway.
37/2015/TT-BCT stipulated content limits and testing procedures for formaldehyde and banned cleavable aromatic amines from azo dyes in textile products as well as inspection requirements.
Hellberg, Ortho Ester-Based Cleavable Cationic Surfactants, J.
Tom20 and Tom22 mainly recognize the presequences of cleavable precursor proteins, while Tom70 typically largely recognizes the internal targeting signals of hydrophobic precursor proteins, many of which are inner membrane metabolite carriers [58].
This claim has been demonstrated in the research of Auzely-Velty and Rinaudo (2003), for the synthesised starch betaine derivatives using disopropylcarbodiimide and 4-dimethylaminopyridine as coupling agents in an aprotic polar solvent, which carry cleavable cationic groups derived from naturally occurring glycine-betanine.
They also showed that the potency of these drugs to stimulate topo II cleavable complexes correlated with their ability to undergo Michael addition (Wang et al.
Preparation of in-vivo cleavable agglomerated liposomes suitable for modulated pulmonary drug delivery.