clinical trial

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Related to clinical trial: Randomized clinical trial, Clinical research
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Noun1.clinical trial - a rigorously controlled test of a new drug or a new invasive medical device on human subjects; in the United States it is conducted under the direction of the FDA before being made available for general clinical use
trial, run, test - the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial"
phase I, phase I clinical trial - a clinical trial on a few persons to determine the safety of a new drug or invasive medical device; for drugs, dosage or toxicity limits should be obtained
phase II, phase II clinical trial - a clinical trial on more persons than in phase I; intended to evaluate the efficacy of a treatment for the condition it is intended to treat; possible side effects are monitored
phase III, phase III clinical trial - a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA
phase IV, phase IV clinical trial - sometimes the FDA approves a drug for general use but requires the manufacturer to continue to monitor its effects; during this phase the drug may be tried on slightly different patient populations than those studied in earlier trials
References in periodicals archive ?
Phase Forward has made significant progress in developing technology that can support an integrated clinical trial environment and is well qualified to help us execute this vision.
a recently completed phase 3 hepatitis B clinical trial in Japan, a phase 2 malignant melanoma clinical trial in Europe, and two ongoing phase 2 liver cancer pilot studies in the U.
In Progress Trials by Phase 22 Clinical Trials by Trial Status 23 Clinical Trials by End Point Status 24 Unaccomplished Trials of Cardiomyopathy 25 Subjects Recruited Over a Period of Time 28 Clinical Trials by Sponsor Type 29 Prominent Sponsors 30 Top Companies Participating in Cardiomyopathy Therapeutics Clinical Trials 31 Prominent Drugs 32 Clinical Trial Profiles 33 Clinical Trial Overview of Top Companies 33 Johnson & Johnson 33 Clinical Trial Overview of Johnson & Johnson 33 Gilead Sciences, Inc.
3) Data from the Phase III clinical trial is currently expected to
In August 2002, the Companies initiated an open-label Phase II clinical trial evaluating ERBITUX monotherapy in 250 patients with EGFR-positive metastatic colorectal cancer who have failed or are intolerant to available chemotherapy treatment.
Medical product manufacturers continue to face mounting time-to-market pressures, making the adoption of technology-enabled clinical trial processes imperative.
By working together, we can bring the clinical trial process into the 21st century and enable drug makers to get needed treatments to patients faster.
30, 2015 /PRNewswire-iReach/ -- The report " Steatohepatitis Global Clinical Trials Review, H1, 2015" provides data on the Steatohepatitis clinical trial scenario.
For example, in the early recruitment period for the clinical trials, it was estimated that less than 1 percent of patients with metastatic breast cancer who received an ABMT did so within the context of a randomized clinical trial.
Central Coding for InForm automatically standardizes clinical trial data input to provide cleaner data more quickly and efficiently for organizations conducting clinical trials.
Data on the number of clinical trials conducted in North America, South and Central America, Europe, Middle-East and Africa and Asia-pacific and top five national contributions in each, along with the clinical trial scenario in BRIC nations
While the patient may not benefit directly from the clinical trial, the data regarding the safety and effectiveness generated during the study will certainly benefit future generations of patients, and will serve society as a whole.

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