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Related to clomipramine: Clomipramine hydrochloride


A tricyclic antidepressant drug, C19H23ClN2, used in the form of its hydrochloride salt primarily to treat obsessive-compulsive disorder.

[c(h)lo(ro)- + (i)mipramine.]
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Noun1.clomipramine - a tricyclic antidepressant drug
tricyclic, tricyclic antidepressant, tricyclic antidepressant drug - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
References in periodicals archive ?
Marks IM, Stern RS, Mawson D, Cobb J, and MC Donald R: Clomipramine and exposure for obsessive-compulsive rituals.
Treatment--behavioural and pharmacological (for excessive sleepiness and cataplexy) Behavioural Ensure good sleep hygiene (avoid sleep deprivation) Consider use of strategic napping Pharmacological: For excessive sleepiness Methylphenidate Amphetamine Modafinil Selegiline (also anti-cataplectic) Pharmacological: For cataplexy Gamma-hydroxybutyric acid/sodium oxybate Protriptyline Desipramine Imipramine Clomipramine Venlafaxine Duloxetine Selective serotonin reuptake inhibitors
A meta-analysis of randomised controlled trials in children and adolescents with OCD found clomipramine to be superior to other SRIs.
clomipramine sponsored by GlaxoSmithKline, 75% of the subjects had an adverse effect on paroxetine, 21% had a severe adverse effect, and 13% committed a suicidal act (1 in 8).
These three medications differ in their side effect profiles, with clomipramine (Anafranil) having a greater frequency and severity of adverse effects compared to fluoxetine (Prozac) and fluvoxamine (LUVOX).
The patients, aged between 16 and 65, were given Clomipramine along with the standard treatment for their tumour.
In another study, 46 outpatients suffering from panic disorder found that regular aerobic exercise produced significant clinical improvement of their condition, though it was not as effective as treatment with clomipramine, a drug of proven efficacy against the disorder.
After neonatal treatment with antidepressants, such as clomipramine and desipramine, adult rats show alterations in sleep, sexual activity, and other behaviors that appear to mimic those seen in depressed patients.
xx Aventyl, Budeprion SR, bupropion, Celexa, clomipramine, desipramine, Desyrel, Effexor, Effexor XR, Elavil, Emitrip, fluoxetine, fluvoxamine maleate, imipramine, Lexapro, Ludiomil, Luvox, maprotiline, mirtazapine, nefazodone, Norpramin, nortriptyline, Pamelor, paroxetine, Paxil, Paxil CR, Pexeva, Prozac, Prozac Weekly, Remeron, Serzone, Surmontil, Tofranil, Tofranil-PM, Trazodone, Vivactil, Wellbutrin, Wellbutrin SR, Wellbutrin XL, Zoloft Diabetes 250.
Some of the most frequently prescribed tricyclics are amitriptyline (Elavil), desipramine (Norpramin), clomipramine (Anafranil), doxepin (Sinequan), imipramine, (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil) and trimipramine (Surmontil).