coagulation factor


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coagulation factor

n
(Biochemistry) med another name for clotting factor
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
clotting factor
plasma protein - any of the proteins in blood plasma
factor I, fibrinogen - a protein present in blood plasma; converts to fibrin when blood clots
factor II, prothrombin - a protein in blood plasma that is the inactive precursor of thrombin
factor III, thrombokinase, thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
calcium ion, factor IV - ion of calcium; a factor in the clotting of blood
accelerator factor, factor V, proaccelerin, prothrombin accelerator - a coagulation factor
cothromboplastin, factor VII, proconvertin, stable factor - a coagulation factor formed in the kidney under the influence of vitamin K
antihaemophilic factor, antihaemophilic globulin, antihemophilic factor, antihemophilic globulin, factor VIII, Hemofil - a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
Christmas factor, factor IX - coagulation factor whose absence is associated with hemophilia B
factor X, prothrombinase - coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors
factor XI, plasma thromboplastin antecedent - coagulation factor whose deficiency results in a hemorrhagic tendency
factor XII, Hageman factor - coagulation factor whose deficiency results in prolongation of clotting time of venous blood
factor XIII, fibrinase - in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
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References in periodicals archive ?
Additional factor treatment may not be needed for people on Hemlibra undergoing certain minor surgeries A retrospective analysis of pooled data across the HAVEN studies suggest that people with hemophilia A with and without factor VIII inhibitors may not need additional preventative (prophylactic) coagulation factor (factor VIII replacement therapy or bypassing agents) when undergoing certain minor surgery.
Chugai Pharmaceutical Co., Ltd. - Further Clinical Data including Long-Term Follow-up for Chugai's Hemlibra Presented at ISTH -- 9/7/2019
Octaplas is a S/D treated, virus inactivated, blood group-specific human plasma prepared from pooling multiple single donor FFP units resulting in a standardized composition with significantly lower variability in coagulation factor content compared to standard FFP.
FDA Approves New Octaplas Product Label
Familial multiple coagulation factor deficiencies--chance associations and distinct clinical disorders.
Combined Factor V and VIII Deficiency
The Blood Coagulation Factor balance in healthcare organizations was 118,250 IU at the end of 2017.
114 children suffer from hemophilia in Kyrgyzstan
Interestingly, LPS was able to activate the expression of factor X, a coagulation factor, which increased by 7.5-fold (n = 4) in microglia of LPS-treated animals compared to control (Figure 1(a)).
Thrombin Inhibition Reduces the Expression of Brain Inflammation Markers upon Systemic LPS Treatment
Acquired coagulation factor V (FV) inhibitors are rare and their presentations varied.
Factor V Inhibitors: A Diagnostic and Therapeutic Challenge
Falsely increased PT/INR values could lead to unnecessary transfusions of plasma or coagulation factor concentrates, or they could lead to subtherapeutic anticoagulation with vitamin K antagonists (VKA) like warfarin.
Commentary
Visit Hemophilia Treatment Market by Drug Type (Antifibrinolytic Agents, Desmopressin, Plasma Derived Coagulation Factor Concentrates - Factor VIII, Factor IX, Combination, Recombinant Coagulation Factor Concentrates - Factor VIII, Factor IX, Combination), Indication Type (Acquired Hemophilia, Hemophilia A, Hemophilia B, Hemophilia C), and Distribution Channel (E-commerce, Hospital Pharmacies, Retail Pharmacies) and Forecast 2017-2021 at https://www.ihealthcareanalyst.com/report/hemophilia-treatment-market/
Hemophilia Treatment Market by Drugs, Distribution Channels, Trends and Forecast to 2021, Upcoming Research by iHealthcareAnalyst, Inc.
Objective: To provide a comprehensive literature review on roles of coagulation factor XIII (FXIII) in coagulation, wound healing, neoplasm, bone metabolism, and pregnancy.
Advances of Coagulation Factor XIII
Current opinions suggest that the pathogenesis is multifactorial and mechanisms like activation of the protein C pathway, endothelial injury, coagulation factor deficiency, hyperfibrinolysis, and platelet dysfunction participate in the development of TIC [6-8].
Overexpression of miR-24 Is Involved in the Formation of Hypocoagulation State after Severe Trauma by Inhibiting the Synthesis of Coagulation Factor X
CSL Behring received approval from the FDA for IDELVION [Coagulation Factor IX (Recombinant), Albumin Fusion Protein], its novel, long-acting albumin fusion protein linking recombinant coagulation factor IX with recombinant albumin for the treatment of hemophilia B.
Genentech, a member of the Roche Group, received approval from the FDA for Gazyva (obinutuzumab) plus bendamustine chemotherapy followed by Gazyva alone as a new treatment for people with follicular lymphoma who did not respond to a Rituxan (rituximab) regimen

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