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 (kō-băl′ə-mĭn) also co·bal·a·mine (-mēn′)


(Biochemistry) vitamin B12

vitamin B1


vitamin B2


vitamin B3


vitamin B6


vitamin B12

a complex water-soluble solid, C63H88N14O14PCo, obtained from liver, milk, eggs, fish, oysters, and clams: a deficiency causes pernicious anemia and disorders of the nervous system. Also called cyanocobalamin, cobalamin, extrinsic factor.


ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cobalamin - a B vitamin that is used to treat pernicious anemiacobalamin - a B vitamin that is used to treat pernicious anemia
B complex, B vitamin, B-complex vitamin, vitamin B, vitamin B complex, B - originally thought to be a single vitamin but now separated into several B vitamins
References in periodicals archive ?
Multiple linear regression was used to investigate the association of cobalamin with fasting blood sugar level after adjusting for gestational age and gravidity.
Neuropsychiatry disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis.
Hyperhomocysteinemia and elevated methylmalonic acid indicate a high prevalence of cobalamin deficiency in Asian Indians.
Performance of the serum cobalamin assay for diagnosis of cobalamin deficiency.
Results showed all markers of vitamin B12 status with the exception of plasma cobalamin were significantly associated with the total ASQ-3 scores in the multiple regression models.
2) In children, for example, mutations in the gene encoding the methylmalonic aciduria and homocystinuria type C (MMACHC) have been identified that result in abnormal cobalamin C metabolism, termed cobalamin C disease, which in turn has been associated with endothelial dysfunction, platelet activation, coagulation cascade activation, and increased expression of tissue factor.
Plasma amino acids were also within reference intervals, excluding a combined disorder of cobalamin and homocysteine metabolism, such as cblC, cblD, or cblF types.
Abbreviations A[beta]: Amyloid-[beta] AdoCbl: Adenosylcobalamin BSO: Buthionine sulfoximine Cbl: Cobalamin CNCbl: Cyanocobalamin EAAT3: Excitatory amino acid transporter 3 EGF: Epidermal growth factor GSCbl: Glutathionylcobalamin GSH: The reduced glutathione GSSG: The oxidized glutathione HCY: Homocysteine IGF-1: Insulin-like growth factor 1 MeCbl: Methylcobalamin MS: Methionine synthase NAC: N-Acetylcysteine NRG-1: Neuregulin 1 OHCbl: Hydroxocobalamin PI3K: Phosphatidylinositol 3-kinase PLM: Phospholipid methylation PV+: Parvalbumin-expressing SAM: S-Adenosylmethionine SAH: S-Adenosylhomocysteine S[O.
It was reported that cobalamin had potent superoxide scavenging ability.
The data collected was analysed and a multivariate analysis was done to determine correlation between symptoms, signs and hematological investigations including Bone Marrow aspiration, serum folate and cobalamin assays and Upper GI Endoscopy.