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 (kŏl′chĭ-sēn′, kŏl′kĭ-)
A poisonous alkaloid, C22H25NO6, that is obtained from the autumn crocus and inhibits microtubule formation. It is used in medicine to treat gout and in plant breeding to produce polyploid plants.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈkɒltʃɪˌsiːn; -sɪn; ˈkɒlkɪ-)
(Biochemistry) a pale-yellow crystalline alkaloid extracted from seeds or corms of the autumn crocus. It is used in the treatment of gout and to create polyploid plants by inhibiting chromosome separation during meiosis. Formula: C22H25NO6
[C19: from colchicum + -ine2]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈkɒl tʃəˌsin, -sɪn, ˈkɒl kə-)

a pale yellow, crystalline alkaloid, C22H25NO6, the active principle of colchicum.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.colchicine - an analgesic drug derived from the saffron plant and used to treat gout
analgesic, anodyne, pain pill, painkiller - a medicine used to relieve pain
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n colchicina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
-- The drug colchicine, used to treat the arthritic condition gout, could potentially reduce complications accompanying metabolic syndrome, a combination of high blood pressure, high blood sugar and other conditions that increase the risk of heart disease and type 2 diabetes, according to researchers at the National Institutes of Health.
The first one was use of colchicine for the FMF treatment in 1972, and the second was identification of the MEFV gene that was responsible for the disease in 1997.
Depending on your medical history, your doctor may prescribe steroids or other medicines to reduce inflammation, such as colchicine (Colcrys).
Although most patients have an uncomplicated clinical course with good prognosis after administration of nonsteroidal anti-inflammatory drugs (NSAIDS), corticosteroids or colchicine, some studies report cases of patients with late diagnosis that required pericardial drainage or even redo surgery (4).
- The US Food and Drug Administration approved Gloperba (colchicine) Oral Solution, 0.6 mg/5 mL for prophylaxis of gout flares in adults, US-based drug development company Romeg Therapeutics said.
If gout sneaks round that first line of defence, I also have a supply of Colchicine which can knock it on the head pretty quickly.
Colchicine, originally extracted from Colchicum autumnale, is an anti-inflammatory drug that has been in continuous use for more than 3,000 years.
In this study, all subjects receive a loading dose of rilonacept 320 mg subcutaneously, or SC, followed by 160 mg SC weekly maintenance on top of any combination of co-administered nonsteroidal anti-inflammatory drugs, or NSAIDs, and/or colchicine and/or corticosteroids during a 6-week base treatment period.
Some of the compounds and their derivatives such as paclitaxel, vinblastine, vincristine, etoposide, artemisinin, cannabinoid, resveratrol, camptothecin, derivatives of colchicine (Democolcine, N-deacetylcolchicine, and trimethyl colchicinic acid) are secondary metabolites used as chemotherapeutics in the clinic (3,6,8).
Diagnosis is often based on clinic symptoms, ethnic origin, family history, and colchicine response.[1] Herein, we report a female case who was admitted with recurrent muscle pain and skin rash and diagnosed with FMF based on the presence of an unrecognized skin lesion on physical examination.
The amphidiploid plants of some interspecific hybrid genotypes were obtained by 0.03% colchicine application.