collagenase


Also found in: Thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia.

col·lag·e·nase

 (kə-lăj′ə-nās′, -nāz′, kŏl′ə-jə-)
n.
Any of various enzymes that catalyze the hydrolysis of collagen and gelatin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

collagenase

(ˈkɒlədʒəˌneɪz)
n
(Biochemistry) an enzyme that decomposes collagen
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.collagenase - any enzyme that catalyzes the hydrolysis of collagen and gelatin
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Mentioned in ?
References in periodicals archive ?
The Vivo nanofat was prepared by digesting the rinsed fat tissue with 1 ml of 0.2 mg/ml collagenase I (Sigma, Germany) resuspended to a final volume of 20 ml and incubated at 37[degrees]C for 15 min (we designed a short-time digestion process to save the viability of the adipocytes).
The degradation assay lasted for 4 hours and every 30 minutes measurements were conducted to check the resistance of the gels to degradation induced by the collagenase solution.
The minced tissue was enzymatically digested by a mixture of trypsin, DNase I, and collagenase IV at 37[degrees]C for 30 min under shaking conditions.
McCulloch, "Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: role of active enzyme in human periodontitis," Journal of Periodontal Research, vol.
The residual tissue was washed with PBS, digested with collagenase again at 4 AdegC overnight, and then processed as described above.
Xiaflex is purified collagenase clostridium histolyticum, isolated and purified from the fermentation of Clostridium histolyticum bacteria (Endo Pharmaceuticals, Inc., 2017).
Studies on neutrophil collagenase and MMP-18 in clear cell renal cell carcinoma did not demonstrate any increase in their activity in primary tumour tissue or metastases as compared to normal tissue [3,32].
The elevation of cortisol inhibits fibroblast function and increases matrix metalloproteinases (collagenase, gelatinase).
Collagenase MMP-1, MMP-13, and, in particular, collagenase 2 (MMP-8) play a special role in inflammatory and destructive processes in periodontium since the substrates for these enzymes are collagen types I, II, III, and IV which are important proteins of periodontal attachment apparatus and the soft tissues around implants [19-21].
Bacterial endotoxin (Sigma, L2630, 10 mg), type I collagenase (Sigma, lot number: C0130), Masson staining kit (Beijing Reagan, lot number: DC0032), rabbit TNF-[alpha] kit (R&D Systems subpackage, rb201510200842), IL-1[beta] kit (R&D Systems subpackage, rb201510190821), and IL-4 kit (R&D Systems subpackage, rb201510270951) were the major agents used in this study.
The overall objective of this study was to evaluate the effect of enzyme exposure, incubation time, and additional physical agitation cycles in optimizing chondrocyte isolation from nasal cartilage biopsies using the commonly employed collagenase enzyme.