High-grade CIN lesions identified colposcopically
and/or histologically are conventionally excised.
There were 8 Low-grade squamous intraepithelial lesion (LSIL) reported in the study group of which only two were colposcopically
In 29 cases, which were colposcopically
reported as RCI 0-2, 1 case was histologically confirmed as LSIL/CIN1 (3.44%), 1 case as HSIL (3.44%) and 27 cases were negative for dysplasia (93.10%).
This could be related to some factors that have a potential effect on accuracy like the prevalence of disease, verification bias when no biopsies are taken from colposcopically
negative sites on the cervix, inclusion of LSIL in the definition of abnormal, and whether the colposcopic impression or the biopsy is used as the end point .
Boonlikit, "Correlation between Reid's colposcopic index and histologic results from colposcopically
directed biopsy in differentiating high-grade from low-grade squamous intraepithelial lesion at rajavithi hospital," Journal of the Medical Association of Thailand, vol.
During the procedure, all colposcopically
abnormal findings were excised, aiming for a tissue depth of at least 6 mm.
Loop excision studies after colposcopy have identified women with CIN 2+ and cancer missed colposcopically
Belinson et al., "Colposcopically
directed biopsy, random cervical biopsy, and endocervical curettage in the diagnosis of cervical intraepithelial neoplasia II or worse," The American Journal of Obstetrics and Gynecology, vol.
Reid's Colposcopic Index (RCI) is a systematic, objective method of colposcopically
grading the severity of premalignant cervical lesions and makes use of four colposcopic signs: lesion margin, color of acetowhitening, blood vessels, and iodine staining (Ferris & Greenberg, 1994).
Although Pap smear screening has a high specificity, only colposcopically
directed biopsies can confirm the exact grade of the lesion.
It is also possible that trauma to the cervical tissue from the insertion of the device "induces local small foci of chronic inflammation and a long-lasting immune response similar to that noted in patients after colposcopically
guided punch biopsies.
Until recently, few experts would have questioned the value of the partnership between cervical cytology screening and treatment of lesions detected on colposcopically