It is a problem when gallstones block the common bile duct
or other ducts (tubes) connecting the gallbladder to other organs.
A newly published article in Lancet Gastroenterology & Hepatology entitled "Optimal dilation time for combined small endoscopic sphincterotomy and balloon dilation for common bile duct
stones: a multicentre, single-blinded, randomised controlled trial" assessed the optimal duration of dilation for combined EST and EPBD for the removal of common bile duct
Likewise, failures in the expression of HNF6, HNF1b or Foxf1 result in alterations in the development of the gallbladder and the common bile duct
. In this way, the morphogenesis of the bile duct is susceptible to presenting anatomical variations that may be habitual but clinically not significant, resulting in reports of accessory hepatic ducts and duplications of the gallbladder (Sadler).
Abbreviations GGT - gamma-glutamyl transferase AST - aspartate aminotransferase ALT - alanine aminotransferase ALP - alkaline phosphatase CT - computed tomography JDD - juxtapapillary duodenal diverticulum The common bile duct
was dilated up to 15.32 mm without intraluminal content (Figure 1).
Following cholecystectomy, the common bile duct
was suspended and then cut.
Although our patient was successfully treated with surgical resection of the common bile duct
with biliary bypass and post-adjuvant chemotherapy with cladribine, she died from complications of sepsis.
With the increasing radiological investigation like MRCP, ERCP and endoscopic ultrasound, it has become easier to diagnose common bile duct
stones preoperatively, however stones can be spilled into the common bile duct
during choleystectomy during retraction at the Hartmann,s pouch as might be the case in 04 patients in our study.
As is well known, for the treatment of choledocholithiasis, although EST and lithotomy may achieve good therapeutic effects, function of the sphincter of Oddi is damaged, resulting in postoperative reflux of duodenal fluid and bacterial contamination in bile, increasing the risks of recurrent common bile duct
stones, reflux cholangitis, and even cholangiocarcinoma.
The AJCC defines perihilar cholangiocarcinoma (Klatskin tumors) as occurring from the right and left hepatic ducts to the common bile duct
. Intrahepatic tumors occur starting in the secondary biliary radicles and distal extrahepatic cholangiocarcinomas arise from the common bile duct
Dr.Faisal Ghani Siddiqui said that sometimes acute Cholecystitis is caused by one or more gallstones getting stuck in the main tube leading to the intestine, called the common bile duct
. In rare cases of chronic Cholecystitis, he said that patients may also receive medicine that dissolves gallstones over a period of time.
The patient has had weight loss, which increases the risk of gallstone formation, and the pain pattern is consistent with passage of a gallstone through the common bile duct
The ventral pancreatic duct and the common bile duct
are linked by their embryonic origins (both originate from the ventral outpouching), which results in the adult configuration of their common entrance into the duodenum at the major papilla (11).