antagonism

(redirected from competitive antagonism)
Also found in: Thesaurus, Medical, Encyclopedia.

an·tag·o·nism

 (ăn-tăg′ə-nĭz′əm)
n.
1. Hostility that results in active resistance, opposition, or contentiousness. See Synonyms at enmity.
2. The condition of being an opposing principle, force, or factor: the inherent antagonism of capitalism and socialism.
3. Biochemistry Interference in the physiological action of a chemical substance by another having a similar structure.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

antagonism

(ænˈtæɡəˌnɪzəm)
n
1. openly expressed and usually mutual opposition
2. the inhibiting or nullifying action of one substance or organism on another
3. (Physiology) physiol the normal opposition between certain muscles
4. (Biology) biology the inhibition or interference of growth of one kind of organism by another
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

an•tag•o•nism

(ænˈtæg əˌnɪz əm)

n.
1. an active hostility or opposition.
2. an opposing force, principle, or tendency.
3. an opposing physiological action, as by one muscle in relation to another.
4. the opposing action of substances, as drugs, that when taken together decrease the effectiveness of at least one of them (contrasted with synergism).
[1835–40; (< French) < Greek]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

antagonism

a contentiousness toward or opposition to others or their ideas; hostility or antipathy. — antagonistic, adj.
See also: Attitudes
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.antagonism - a state of deep-seated ill-willantagonism - a state of deep-seated ill-will  
state - the way something is with respect to its main attributes; "the current state of knowledge"; "his state of health"; "in a weak financial state"
latent hostility, tension - feelings of hostility that are not manifest; "he could sense her latent hostility to him"; "the diplomats' first concern was to reduce international tensions"
state of war, war - a legal state created by a declaration of war and ended by official declaration during which the international rules of war apply; "war was declared in November but actual fighting did not begin until the following spring"
cold war - a state of political hostility between countries using means short of armed warfare
suspicion - the state of being suspected; "he tried to shield me from suspicion"
2.antagonism - the relation between opposing principles or forces or factorsantagonism - the relation between opposing principles or forces or factors; "the inherent antagonism of capitalism and socialism"
oppositeness, opposition - the relation between opposed entities
3.antagonism - an actively expressed feeling of dislike and hostilityantagonism - an actively expressed feeling of dislike and hostility
dislike - a feeling of aversion or antipathy; "my dislike of him was instinctive"
ill will, enmity, hostility - the feeling of a hostile person; "he could no longer contain his hostility"
4.antagonism - (biochemistry) interference in or inhibition of the physiological action of a chemical substance by another having a similar structure
interference, hinderance, hindrance - the act of hindering or obstructing or impeding
biochemistry - the organic chemistry of compounds and processes occurring in organisms; the effort to understand biology within the context of chemistry
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

antagonism

noun hostility, competition, opposition, conflict, rivalry, contention, friction, discord, antipathy, dissension There is much antagonism between the unions and the companies.
love, accord, agreement, friendship, sympathy, harmony, amity, peacefulness
Collins Thesaurus of the English Language – Complete and Unabridged 2nd Edition. 2002 © HarperCollins Publishers 1995, 2002

antagonism

noun
1. Deep-seated hatred, as between longtime opponents or rivals:
The American Heritage® Roget's Thesaurus. Copyright © 2013, 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations
خُصومَة، عِداء
antagonismusnepřátelství
antagonismefjendskab
fjandskapur
antagonizmus
düşmanlıkkin

antagonism

[ænˈtægənɪzəm] N (towards sb) → hostilidad f; (between people) → rivalidad f, antagonismo m
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

antagonism

[ænˈtægənɪzəm] nantagonisme m
racial antagonism → antagonisme des races
class antagonism → antagonisme des classes
antagonism towards sth → hostilité à qch
antagonism towards sb → hostilité envers qn
Collins English/French Electronic Resource. © HarperCollins Publishers 2005

antagonism

n (between people, theories etc) → Antagonismus m; (towards sb, ideas, a suggestion, change etc) → Feindseligkeit f, → Feindlichkeit f(to(wards) gegenüber); to arouse somebody’s antagonismjdn gegen sich aufbringen
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

antagonism

[ænˈtægənɪzm] nantagonismo
Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

antagonist

(ӕnˈtӕgənist) noun
an opponent or enemy.
anˈtagonism noun
unfriendliness, hostility.
anˌtagoˈnistic adjective
anˌtagoˈnistically adverb
anˈtagonize, anˈtagonise verb
to make an enemy of (someone). You are antagonizing her by your rudeness.
Kernerman English Multilingual Dictionary © 2006-2013 K Dictionaries Ltd.
References in periodicals archive ?
After initial resuscitation, the patient was treated with an intravenous infusion of calcium chloride in an effort to overcome the drug's toxic effects by competitive antagonism. The significantly increased free and total calcium concentrations reported from the laboratory were found to be accurate and interestingly therapeutic in nature, rather than reflecting a primary disease state or laboratory error.
This pharmacological method allowed us to assess whether the observed antiandrogenic activity was solely due to competitive antagonism of dihydrotestosterone (DHT) binding to the ligand binding domain of the AR (Kenakin 1993).
PA did not interfere with the activation of P2[Y.sub.1] receptor by MRS2365 to induce platelet shape change and displayed a competitive antagonism of ADP-induced platelet aggregation, which most probably involves competition for a single binding site in platelets.