concanavalin


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concanavalin

(ˌkɒnkəˈnævəlɪn)
n
either of two globulins, concanavalin B or (more commonly) concanavalin A, that occur in the jack bean Canavalia ensiformis. Concanavalin A causes agglutination of the blood of mammals
References in periodicals archive ?
In another study, The entrapped crosslinked concanavalin [alpha]- [beta]-galactosidase complex retained 95 % activity after seventh repeated use (Haider and Husain, 2007).
Apart from oncology, in the immunoregulation area, another of Enzo's research collaborators has shown that SK1-I prevents the induction of Interferon Gamma, a major inflammatory biomarker, in a well-established Concanavalin A induced animal model of autoimmune hepatitis.
In addition to the BEACH domain, the BDCP shares the ConA-like domain (concanavalin A-like), PH (Pleckstrin homology) and WD40 (repeats of tryptophan and aspartic acid) domains.
Lin, Homogeneous detection of concanavalin A using pyrene-conjugated maltose assembled graphene based on fluorescence resonance energy transfer, Biosens.
Concanavalin A (ConA) is a plant agglutinin extracted from Brazilian rubber beans that was firstly used to study liver injury by Tiegs et al.
Concanavalin A (ConA) is a mitogenic plant lectin extracted from Canavalia brasiliensis [2] that has been used to model liver injury in vivo.
Splenic T cells were added at 1 x [10.sup.5] cells/well, and concanavalin A (ConA; 1 [micro]g/ml) was added to activate the cells.
Immunodeficiency workup revealed elevated immunoglobulin levels, protective vaccine titers, and normal lymphocyte counts and response to phytohaemagglutinin, concanavalin A, and pokeweed mitogen.
Concanavalin A- (ConA-) induced hepatitis is an appropriate animal model for drug research and immune-mediated liver injury for human hepatitis [3].
The splenocytes were then cultured with no peptide, 10 [micro]g/ml of concanavalin A (Sigma-Aldrich), 20 [micro]g/ml of [beta]-galactosidase peptide TPHPARIGL (New England Peptide, Gardner, MA), or 10 [micro]g/ml of pooled 15-mer peptides with an 11base overlap spanning the VEEV IAB E2 or E1 envelope glycoprotein (Pepscan, Lelystad, Netherlands) for 24 h at 37[degrees]C with 5% C[O.sub.2].
Protective role of synthetic oligodeoxy-nucleotides expressing immunosuppressive TTAGGG motifs in concanavalin A-induced hepatitis.