Pirog et al (16,17) have found positive Ki-67 (MIB-1) immunostaining, defined as any cluster of at least 2 positive nuclei in the upper two-thirds of the epithelium, in all vulvar and anal condylomas
examined, a finding that correlated well with positive HPV results by polymerase chain reaction (PCR) and DNA sequencing.
She denied any history of HPV, sexually transmitted infections or genital condylomas
. She had not had any abnormal pap smears or irregularities reported on gynecologic exam.
Taken together, approximately 16% of genital HPV-6 and HPV-11 infections progressed to condylomas
with the same HPV type while less than 1% of genital HPV-16 infections progressed to an HPV-16-positive PeIN among Brazilian men.
and intraepithelial neoplasia of the cervix in immune suppressed renal transplant patients have been found to be high risk factors for malignancy.
Although extra-genital condylomas
are rare such large intraoral condylomas
are much rarer.
have also been reported to occur in patients who have genital warts or whose sexual partner has genital warts.
anal intraepithelial neoplasia (AIN).2 Anal and perianal SCC is associated with persistent high-risk HPV infection previous lower genital tract dysplasia/ carcinoma high-frequency anoreceptive intercourse heavy cigarette smoking and immunosuppression.4 Not all perianal SCCs or condylomas
are associated with HPV infection.
Age, y Sex Diagnosis 1 57 M MCC, primary 2 61 F MCC, primary 3 57 F MCC, primary 4 82 F MCC, primary 5 78 M MCC, metastatic 6 80 F MCC, primary 7 65 M MCC, primary 8 81 M MCC, primary 9 60 M MCC, primary 10 61 M Hyperkeratosis 11 49 M Seborrheic keratosis, penis 12 60 M Nonspecific lesion, esophagus 13 40 M Nasal papilloma 14 58 M Anal condylomas
15 44 M Epidermodysplasia verruciformis 16 19 M Cutaneous warts 17 57 F Cutaneous warts 18 64 F Cutaneous nodule 19 6 F Pharyngeal papillomatosis 20 27 M Vocal cord polyp 21 58 M Lichen 22 63 M Skin inflammation 23 72 M Skin inflammation 24 57 M Skin inflammation Patient no.
The laser recently received clearance for use in treating benign prostatic hyperplasia (BPH), adding to its other soft tissue uses, including bladder tumors, condylomas
, the removal of cysts, and warts, biolitec, Inc., 515 Shaker Rd., East Longmeadow, MA 01028.
It is transmitted to the newborn during the delivery process as the child comes through the vaginal tract that is infected with condylomas
, a wart like growth.
In a study published this year of 1,778 HIV-infected women and 500 HIV-negative women followed for 8 years, incident condylomas
were detected in 23% of HIV-positive women vs.
He advised caution about the diagnosis of VAIN-1, "A lot of us are trying not to make low-grade diagnoses of VIN or VAIN," and instead, "classify the majority of these lesions as flat condylomas
, because the natural history of these low-grade lesions is not really well characterized," Dr.