has long received support from FDA, which has been interacting with the European Medicines Agency (EMA) and aligns well with FDA's process analytical technology (PAT) and process validation guidance.
Contract notice: 456 On-going supply, installation and commissioning of continuous processing
Commercial pressures are leading the drive towards continuous processing
to shorten development times, improve efficiency of the development process and to reduce the amount of API used.
It is best to have a gatekeeper at the front of a continuous processing
line checking castings as they leave the shot blast.
Facilitating the switch to continuous processing
was a scraped-surface heat exchanger from Waukesha Cherry-Burrell (WCB), an SPX Process Equipment operation.
Dual-solvent rinsing is available, and an optional temperature-controlled rack changer allows continuous processing
of up to 12 deepwell plates for high-throughput laboratories.
The WJ PRO's short paper path and automatic thickness adjustment for mail up to 5/8" thick ensure efficient, continuous processing
, while minimizing paper jams and postage waste.
Even though many of the same unit processes and unit operations are used in the manufacture of these products, demands and constraints needed for continuous processing
are challenging and would require a totally different set of thinking and business model.
A sophisticated continuous processing
pharmaceutical production line has began operations at Promis Centre located in Kuopio, eastern Finland, which enhances the quality of tablets while speeding up production and cutting costs.
One of the fundamental tenants of lean manufacturing relates to the use of continuous processing
as a game changing methodology to replace more traditional batch processing.
Stratus, ftServer and Continuous Processing
are registered trademarks of Stratus Technologies Bermuda Ltd.
is being practiced in many industries including pharma's older cousin--the chemical industry--for more than sixty years.