With the development of Descemet's membrane endothelial keratoplasty, an excellent clinical outcome is seen in the treatment of corneal endothelial dysfunctions, which indicates that thinner corneal graft
results in better clinical outcome.
Keratoplasty is a surgical procedure whereby diseased cornea is removed and replaced with donor corneal graft
20 It is also being used in high-risk cases of penetrating keratoplasty (PKP) where it is applied along with the corneal graft
Other patients will require specialist contact lenses for conditions including aphakia, pathological high myopia, post corneal graft
surgery, corneal scarring and other ophthalmic conditions.
The different corneal bandaging techniques using contact lenses, collagen based biomaterials, cyano-acrylate tissue adhesives, corneal graft
, third eye lid flap, conjunctival flap and temporary tarsorrhaphy for repair of full thickness defect in cornea has also been described (Miller, 2008).
A cornea transplant is often referred to as a keratoplasty, or a corneal graft
I had eight stitches in my eye with a pioneering square lens replacement through a corneal graft
which has given me 20 per cent vision.
Global Markets Direct's, 'Corneal Graft
Rejection - Pipeline Review, H2 2015', provides an overview of the Corneal Graft
Rejection's therapeutic pipeline.
Regarding the risk factors, 23 patients (45%) were contact lens wearers, 6 (12%) had corneal foreign body, 5 (10%) had recurrent corneal erosion, and 4 (8%) had corneal graft
Severe allergic keratoconjunctivitis (the main indication in general practice), adenoviral keratoconjunctivitis, uveitis, episcleritis, scleritis, corneal graft
rejection, immunogenic keratitis and uveitis.
Clinical studies so far have shown that aganirsen is able to safely and effectively inhibit the development of progressive corneal neovascularisation secondary to infectious keratitis or chemical burns both of which could lead to corneal graft
Due to the nature and size of the corneal graft
, a high degree of astigmatism was present in the right eye, which was corrected by the use of a precisely fitted contact lens.