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Related to cornified: cornified layer


intr.v. cor·ni·fied, cor·ni·fy·ing, cor·ni·fies
To undergo cornification.
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Filaggrin helps to aggregate the cytoskeletal proteins that form the cornified cell envelope.
The animals showing estrous phase (presence of irregular, non-nucleated, and cornified cells) were chosen for the experiment.
5] Studies have demonstrated the pivotal role of epidermal barrier dysfunction in AD; it results in the down-regulation of cornified envelope genes, reduced ceramide levels in the stratum corneum (SC), elevated levels of endogenous proteolytic enzymes, and increased TEWL.
Epidermal keratinocytes in the basal layer of the epidermis move upward and ultimately differentiate into cornified cells in the epidermal stratum corneum, thus forming the epidermal permeability barrier.
PNPLA1 catalyzes the transacylation of LA from triglyceride to [omega]-OH ceramide, leading to the formation of [omega]-O-acylceramide, which is an essential component of lipid lamellae and the cornified lipid envelope in the uppermost epidermis.
Cornified, enucleated cells were also found but in smaller proportion.
46) By the time these cells reach the skin's surface, they become cornified or hornlike, transforming into protein-rich bricks tightly bound together by a layer of mortar composed of various lipids, up to 50% of which are ceramides.
The hair shaft is a cornified structure that protrudes from the follicle above the skin surface.
Moreover, positive filaggrin staining indicated the formation of a cornified layer (Fig.
7] In analyzing these various reasons why carcinoma of the cervix is seen so infrequently with procidentia, the cornified cervical epithelium becoming resistant to the development of carcinoma and less vaginal secretion, absence of infection, and free drainage appear to be the commonest reasons given for the protection against carcinoma.
Both LCE1A and FLG belong to the cornified envelope which was recently shown to be highly involved in redox regulation via ROS quenching [88].
These fungal organisms are adapted to colonize hair and cornified layers of skin where they can digest keratin protein for nutrition.