The appearance of the patient is like a man being confined in a barrel.1 This rare syndrome is associated with cerebral hypoperfusion due to border zone infarcts that are generally present between the anterior and middle cerebral artery irrigation areas.2 In addition to many cerebral lesions with different natural characteristics that cause the upper limb-related fibres of the pyramidal corticospinal
tract to be injured, cervical spinal cord lesions and peripheral nerve diseases may also be present with this disease.3 Herein we presented a patient with MIBS which was due to bilateral brachial plexopathy caused by recurrent microtrauma.
CN VI arises in the pons in close association to CN VII (facial nerve), paramedian pontine reticular formation (PPRF), medial longidutinal fasculiculus (MLF) and descending corticospinal
His work has demonstrated the importance of the spinal input to descending corticospinal
responses modulating pain and motor control.
Meanwhile, our previous cross-sectional study demonstrated that the GM volume of the whole brain did not significantly differ between ALS patients and healthy controls (HCs), though FA in the bilateral corticospinal
tract and corpus callosum was significantly lower in the ALS group than in the HC group, indicating that the microstructural involvement of WM was more prominent than GM damage in ALS patients at baseline.
RAD51 expression was detected in corticospinal
axons at the pyramidal decussation in two-day-old mouse models and its deficiency specifically alters the development of an intact de-cussation tract (14).
[3,4,11] Given the combined nerve innervations of the respiratory muscles and the deltoid, neck flexors and trapezius muscles via the corticospinal
pathway (C1 - C6), [12,13] the question arises whether upper-limb muscle strength and endurance could predict successful extubation in mechanically ventilated patients by means of interneuron activation.
After grafting cultured hPSC-derived NSCs into injured spinal cords of rats, they noted that the grafts were rich in excitatory neurons, which are extended large numbers of axons over long distances, innervated their target structures and enabled robust corticospinal
Spontaneous motor activity is known to be essential for the development of the corticospinal
tract (Clowry, 2007).
After grafting cultured hPSC-derived NSCs into injured spinal cords of rats, they noted that the grafts were rich in excitatory neurons, extended large numbers of axons over long distances, innervated their target structures and enabled robust corticospinal
Diffusion tensor imaging images obtained at the age 14 years revealed the involvement of tegmental to corticospinal
atrophy (Figure 1).
(5) In patients with iNPH, in addition to altered CSF flow, enlarged ventricles compress the corticospinal
tracts in the lateral ventricles, (6) which is theorized to induce PBA symptoms.
The descending corticospinal
tracts and ascending dorsal columns decussate in the medulla while the ascending lateral spinothalamic tracts decussate within one or two levels of the entrance of the dorsal roots.