corticotrophic

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Related to corticotropic: corticotropic hormone

corticotrophic

(ˌkɔːtɪkəʊˈtrəʊfɪk) or

corticotropic

adj
(Biochemistry) stimulating the adrenal cortex; adrenocorticotrophic
References in periodicals archive ?
3] Via the hypophyseal portal circulation CRH reaches the anterior pituitary where, on binding with CRH receptor I, induces adrenocorticotropic hormone (ACTH) release by the pituitary corticotropic cells.
corticotropic cells) to synthesize and secrete a peptide called proopiomelanocortin (POMC).
Systemic increase in corticotropic hormone (CRH), growth hormone-releasing hormone (GHRH), thyrotropin-releasing hormone (TRH), and luteinizing hormone-releasing hormone (LHRH) resulted in an increase in ACTH and prolactin (PRL) levels and a decrease in thyroid-stimulating hormone (TSH).
The hypothalamus produces corticotropic hormone, which stimulates corticotrophs to release ACTH, which then stimulates the adrenal cortex to produce and release cortisol and androgens.
Plasma cortisol decreases the HPA axis activity by negative feedback mechanism, decreasing corticotropic hormone (CRH) in the hypothalamus.
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