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n. Genetics
An artificially constructed plasmid used for cloning large genes or other DNA sequences.

[Blend of cos (sequence), sequence of DNA allowing the cosmid to form as a circle (short for cohesive ends) and plasmid.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


a large plasmid that is used as a cloning vector and is able to clone large segments of DNA
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cosmid - (genetics) a large vector that is made from a bacteriophage and used to clone genes or gene fragments
vector - (genetics) a virus or other agent that is used to deliver DNA to a cell
genetic science, genetics - the branch of biology that studies heredity and variation in organisms
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
ApoE3-Leiden mice were designed by Van den Maagdenberg and co-authors using microinjection of cosmid carrying the desired mutated DNA fragment into male pronuclei of fertilized mouse eggs taken from super-ovulated females (32).
The isolated DNA can be used in a variety of procedure including micro injection into mammalian cells and creation of cosmid and phage sub libraries.
Brady, "Expanding small-molecule functional metagenomics through parallel screening of broad-hostrRange cosmid environmental DNA libraries in diverse proteobacteria," Applied and Environmental Microbiology, vol.
COSMID study showed that all patients were of lipids and off diabetic medications.
Physical assignments of 68 porcine cosmid and lambda clones containing polymorphic microsatellites.
A cosmid library was constructed from the WGA product of a sample containing two bacterial cells, one a member of the candidate phylum Poribacteria and one of a sponge-specific Glade of Chloroflexi.
A cosmid DNA library was constructed by using pWEB kit (Epicenter Biotechnologies, Madison, WI, USA) by following protocols described elsewhere (7).
A cosmid clone, pOK40, which complements the mutant K818, was isolated from a genomic library of the parent strain.
Interphase molecular cytogenetics of Ewing's sarcoma and peripheral neuroepithelioma t(11;22) with flanking and overlapping cosmid probes.
Identification of Mycobacterium leprae from a cosmid library: characterization of a kilodalton antigen that is recognized by both humoral and cellular immune system in leprosy patients.