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An agent that induces local inflammation to relieve inflammation in underlying or adjacent tissues.
Of or producing the effect of such an agent.

coun′ter·ir′ri·ta′tion (-tā′shən) n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pharmacology) an agent that causes a superficial irritation of the skin and thereby relieves inflammation of deep structures
(Pharmacology) producing a counterirritation
ˌcounterˌirriˈtation n
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌkaʊn tərˈɪr ɪ tənt)

1. an agent for producing inflammation in superficial tissues to relieve pain or inflammation in deeper structures.
2. of or acting as a counterirritant.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.counterirritant - a medicine applied locally to produce superficial inflammation in order to reduce deeper inflammation
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
In addition, menthol is present in pharmaceutical preparations that are used as cooling agent in the counterirritant rubefacients, mouth and throat antiseptics, hemorrhoids, and many other pharmaceutical formulation [5-7].
The company notes that its new Atomic Heat product features two active ingredients: capsaicin, a compound that occurs naturally in chili peppers, and methyl salicylate, which is a counterirritant that causes the skin to feel cool and then warm.
Cayenne contains capsaicin, which acts as a counterirritant (it initially causes a mild burning sensation, but then silences local pain nerves).
(34) This type of action probably contributes to the counterirritant or rubifacient effects of various warming or pungent plants used topically for symptomatic relief in inflammatory muscle or joint pain.
"NEVER in the history of football has a season opened under such gloom as the one on the threshold of which we now stand, and never before has the great national game had such an opportunity of justifying its hold on the public as a recreative sport and a beneficial counterirritant to the anxieties of this workaday world." Such was the dilemma facing football clubs " on the eve of the 1914-15 season.
Physical effects of this therapeutic resource are based on the reduction of skin temperature from the rapid evaporation of colloids that act as a counterirritant (GREEN, 1991), inhibiting thus pain impulses (ALGAFLY; GEORGE, 2007), working as an analgesic / or local anesthetic (REIS; HOLUBKOV, 1997), reducing muscle spasms and promoting early mobilization (HALKOVICH et al., 1981).
It has traditionally been used as a topical rubefacient and counterirritant to relieve pain of muscles and joints.
When used topically, it acts as a counterirritant and analgesic with the ability to reduce pain and tension.
The butter is also used as a counterirritant and for treating rheumatism.
Unrefined castor oil, also called the Palma Christi, contains ricin from the castor bean, a counterirritant with marvelous lymphatic-stimulating and pain-relieving properties.