coxib


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coxib

(ˈkɒksɪb)
n
an anti-inflammatory drug
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
In fact, while other agents have been shown to raise blood pressure between 4 and 6% in hypertensives, one coxib in particular appears to raise it by some 25 to 30%.
Celecoxib (Celebrex[R]) and role coxib (Vioxx[R]) are COX-2 inhibitors which have been marketed widely, directly to the public through the media when the safety of rofecoxib was questioned.
Their rate of hip, pelvis, wrist, or humerus fractures was 101 per 1,000 person-years, compared with 19 per 1,000 person-years in the coxib group and 26 per 1,000 person-years in the NSAID group.
Or, similarly, for a new coxib thought to be less harmful on the gastrointestinal tract than the best other remedy on the market, the scientific methodology would require enrollment of people who already have peptic ulcer disease.
In contrast to "coxib" and other mislabeled "anti-inflammatory" drugs that consistently elevate the incidence of cardiovascular disease, death, and other adverse effects, (284-288) supplementation with chondroitin sulfate appears to safely reduce the pain and disability associated with osteoarthritis while simultaneously reducing incidence of cardiovascular morbidity and mortality.
(6,7) One of these, the Coxib and Traditional NSAID Trialists' (CNT) Collaboration concluded: "The vascular risks of high-dose diclofenac, and possibly ibuprofen, are comparable to coxibs, whereas high-dose naproxen is associated with less vascular risk than other NSAIDs.
You prescribe a coxib (a cyclo-oxygenase-2 inhibitor) and recommend a proton pump inhibitor.
The propensity matching was meticulous in this study, leading to well-balanced baseline characteristics among the three treatment groups, This reassures readers that the observational study design is as robust as possible, and that treatment effects alone account for the observed differences among opioid, NSAID, and coxib users.
The sponsors of MEDAL programme (4) conducted an analysis of 3 RCTs to assess the safety of etoricoxib (the newest coxib on the market) versus diclofenac in 34 701 patients with arthritis.
"This is now a phenomenon that I think is greater than a coxib issue, even though we clearly had the first signs from a coxib," he said.