Its anatomic variants include imperforate, pinhole (micro perforate), septate and cribriform
.5 Microperforate is a rare form and frequently mistaken for an imperforate hymen.
The ethmoid bone consists of four parts: horizontal (cribriform
) plate, vertical (perpendicular) plate, two lateral masses (labyrinths).
Gleason pattern 4 includes poorly formed, fused, and cribriform
Over the years, all cribriform
patterns were shifted from GP 3 to GP 4, so that by the 2014 ISUP consensus, GP 3 was left with well-formed gland pattern only.
Hymenal anatomic variants include microperforate, septate, or cribriform
. They occur secondary to incomplete degeneration of the central portion of the hymen.
However, the final histological analysis showed that this tumor consisted of epithelial and myoepithelial cells appearing in tubular and cribriform
Histopathology demonstrated a large cyst lined by either papillary projections or a single layer of cuboidal cells with mild to moderate atypia and surrounding solid tumor nests with focal cribriform
pattern [Figure 3a-c].
Rohen6 examined 400 trabeculectomy specimens of glaucomatous eyes with ultra-structural analysis and found, three types of extracellular deposits containing glycoproteins within the cribriform
layers of the trabecular meshwork.
Pleomorphic adenoma, low-grade mucoepidermoid carcinoma, acinic cell carcinoma, myoepithelial carcinoma low-grade cribriform
cystadenocarcinoma, oncocytic carcinoma and salivary duct carcinoma.
Hematogenous metastases to the lungs are most commonly being found at late stage, but rarely spreading to local lymph node. Histologically, the tumor consisted of cribriform
, tubular, and solid formations of atypical epithelial cells with dark compact angular nuclei and frequent mitotic figures. The cribriform
pattern is the most common and has the best prognosis, whereas the solid type is less frequent and has a poorer prognosis.
Areas with epithelial cell proliferation were observed to be composed of uniformly cribriform
patterned round cells with relatively increased nucleus-to-cytoplasm ratios, without nucleoli specificity (Figure 1).
Adenoid cystic carcinoma (ACC) is a malignant salivary gland tumor that was first described by Billroth in 1859 and gave the term cylindroma attributing to its cribriform
appearance formed by the tumor cells with cylindrical pseudolumina or pseudospaces.