"Corneal
cross-linking is beneficial to my patients in that if offers them a therapeutic option to limit the progression of keratoconus," says Dr.
The performance of SAP synthesis processes are influenced by many reaction variables such as cross-linker type and concentration, initiator type and concentration, monomer(s) type and concentration, polymerization method, reaction temperature, amount and type of the surfactant used, reactor geometry and agitation, drying temperature and time, and surface
cross-linking. In a typical industrial solution SAP process, which is currently the most commonly employed industrial manufacturing process, the polymerization is carried out in an aqueous medium at relatively low temperatures in presence of watersoluble free radical initiator [2].
So, Korean scientists used ethanol heat and
cross-linking heat treatments to make AGPS.
M2 PHARMA-March 19, 2018-Avedro and FDA Agree on Design for Phase 3 Trial of Epi-on
Cross-Linking Treatment of Progressive Keratoconus
While there are various strategies for the synthetic modification of cellulose,
cross-linking is known to alter the physicochemical properties due to pillaring effects [4,5].
Many studies have shown that sclera riboflavin/UVA collagen
cross-linking can effectively enhance biomechanical strength of the sclera and could potentially be one of the most promising methods for treating pathological myopia [1-4].
Studies have shown that the dissolved solids can affect the gelation and
cross-linking of the gel and thus reduce its viscosity and elasticity [22-25].
Conventional polyolefin based polymers (high and low density polyethylene and ultra-high molecular weight polyethylene) have been recently studied for the development of composites with CNTs due to their low cost, good processability, and
cross-linking efficiency.
Recently transepithelial
cross-linking, gained rounds by leaving epithelium intact, improving patient comfort and minimizing the risk of infection associated with epithelial removal.6
For the purpose of avoiding these identified problems, it has been resorted to methods such as
cross-linking and the blending with other polymers with better mechanical properties.
Although topical antifungal therapy continues to be the gold-standard for treatment worldwide, photoactivated chromophore for keratitis-corneal collagen
cross-linking (PACK-CXL) has been explored as an option for decreasing the likelihood of complications, specially corneal perforation.
