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(krôs′rē-ăk′shən, krŏs′-)
The reaction between an antigen and an antibody that was generated against a different but similar antigen.

cross′-re·act′ v.
cross′-re·ac′tive adj.
cross′-re·ac·tiv′i·ty n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


an immunologic reaction between a given antigen and an antibody or lymphokine that is specific for a different antigen.
cross′-reac′tive, adj.
cross`-reactiv′ity, n.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive ?
Conversely, at achievable concentrations of piperacillin-tazobactam in serum we did not observe any cross-reaction with this antibiotic.
This program determined that a key issue facing WNV diagnostics was false positives due to cross-reaction of antibodies to closely related flaviviruses.
Tests for penicillin allergy in man: The immunological cross-reaction between penicillins and cephalosporins.
Specificity was based on the polypeptide target size (diagnostic molecular mass) and the absence of cross-reaction with polypeptides from either BT products or vegetative B.
In addition, the cross-reaction is stronger in dark-adapted animals than in light-adapted animals.
These findings demonstrate that some, but not all, immunoassay reagents used for the detection of THC metabolite are susceptible to cross-reaction errors resulting from the presence of EFV (metabolite) in human urine.
This assumption remains unsupported because the SFTS assay has not been evaluated for cross-reaction with antibodies to other non-SFTS members of the genus Phlebovirus (1,3).
Fenugreek gives a stronger cross-reaction to peanut than other legumes.
Now, experiments performed at Duke University Medical Center in Durham, N.C., rule out such a cross-reaction scenario.
Effective concentration of hCG [beta] cf (pmol/mol creatinine) attributable to cross-reaction at a molar cross-reactivity of: LH [beta] cf, 10% 5% pmol/mol creatinine Mean urinary LH [beta] cf et al.
Subsequent studies demonstrated that much of this immunoreactive [beta]-core could be attributed to cross-reaction with a metabolite of LH, which we termed [beta]-LH-core and which was almost certainly produced by the same degradation pathways that led to hCG[beta]cf (19).