We also just received our fourth Qualified Infectious Disease Product (QIDP) designation with Fast Track status from the FDA for MAT2203 for the treatment of cryptococcal
Food and Drug Administration has designated MAT2203, Matinas' proprietary oral amphotericin B product, as a Qualified Infectious Disease Product with Fast Track status for the treatment of cryptococcal
A life-saving drug for people living with HIV is missing in most high traffic HIV clinics in the country, the Nation has learnt.The drug, liposomal amphotericin B (L-AMB), is highly effective when used in combination with other medicines to treat cryptococcal
meningitis, the second biggest killer of people living with HIV after tuberculosis.
Meningitis is included in the US FDA's tropical disease priority review voucher programme.
Pre-emptive antifungal therapy: in adults and adolescents, if blood cryptococcal
antigen screening positive among people with CD4 counts <100 cells/[micro]l (where lumbar puncture is negative or not feasible or if lumbar puncture excludes cryptococcal
This molecular type is the causal agent of cryptococcal
disease in immunocompromised patients, particularly with HIV/AIDS (3,16,27-29).
Background: The incidence of cryptococcal
meningitis among immunocompetent patients increases, especially in China and imaging plays an important role.
Fifteen patients with cryptococcal
meningoencephalitis were evaluated in the study (Table 1).
CSF opening pressure (OP) readings are a vital component of LPs and results often play an important role in guiding both diagnosis and management of patients with conditions such as cryptococcal
meningitis, tuberculous meningitis, pseudotumour cerebri and normal-pressure hydrocephalus.
Results: Tuberculous meningitis was the most common presentation as secondary CNS illness (49%), followed by cryptococcal
meningitis (16%) and cerebrovascular accidents (7%).
infection resulting in acute respiratory distress syndrome (ARDS) as the initial clinical presentation of AIDS.