17) However, IPC is characterized by the presence of papillary fronds lined by cuboidal
cells that often reveal higher-nuclear-grade cytology.
Microscopic examination of tissues revealed a mass that expanded the bronchial lumen and was composed of papillary proliferations of rows of small cuboidal
epithelial cells that were small and uniform in size with a low mitotic index.
2) They felt the histologic appearance of the tumors was most consistent with an origin from columnar or cuboidal
epithelium, with limited nonmucous secretoryactivity.
Simple hyperplasia of reactive mesothelium is usually not confused with malignancy and, as the name implies, consists of a single row of regularly spaced, cytologically bland, cuboidal
mesothelial cells along the pleural surface (Figure 3).
Histopathologic examination revealed that the cyst was formed by a thick, well vascularized connective tissue wall lined by a disorganized, pseudostratified, low cuboidal
to stratified squamous epithelium that was eroded multifocally.
The tissue was composed of papillary epithelial outgrowths with a fibrovascular stroma and an epithelial covering that was cuboidal
to columnar (figure 2, B).
Simple atrophy is easily detectable on low magnification owing to its basophilic appearance imparted by the scant cytoplasm of the low cuboidal
to flattened cells populating the glands.
Neoplastic cells were cuboidal
to polygonal, with variable degrees of squamous differentiation and cornification toward the center of nests.
The lumens were lined with cuboidal
and columnar epithelium with an outer layer of spindle-type and clear cells.
The cysts are usually unilocular and oval to round with a smooth outline and lined by a single layer of flattened to cuboidal
epithelium, often filled with transudate-like clear or straw-colored fluid.
Potassium iodide causes involution, as follicular cells revert to their normal cuboidal
or flattened appearance, alternating with areas that have retained some of the features of hyperplasia (figure 3, A).
Minor criteria include glands with (1) right-angle branching or (2) smooth, rounded outlines; and (3) 2 cell populations with an outer perimeter cell group composed of tall, pleomorphic, and mitotically active cells that stain poorly for prostate-specific antigen (PSA), and a central group that is cuboidal
, monomorphic, and quiescent, with abundant cytoplasm containing abundant PSA and occasional extracellular mucin.