Cushing's syndrome

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Cushing syndrome

or Cushing's syndrome
n.
A group of symptoms, including a puffy face, fat accumulation around the torso, fat loss from legs and arms, and easy bruising, resulting from elevated levels of cortisol in the bloodstream that are caused either by excess production of the hormone ACTH, as from an adrenal or pituitary tumor, or by administration of high doses of corticosteroid hormones. Cushing syndrome caused by a pituitary tumor is called Cushing disease.

[After Harvey Williams Cushing.]

Cushing's syndrome

A condition caused by oversecretion of glucocorticoid hormones from the adrenals, resulting in a redistribution of body fat and other effects.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Cushing's syndrome - a glandular disorder caused by excessive cortisol
adenosis, gland disease, glandular disease, glandular disorder - a disorder of the glands of the body
Translations

Cushing's syndrome

n. síndrome de Cushing, síndrome adrenogenital asociado con una producción excesiva de cortisol, caracterizado por obesidad y debilitamiento muscular.
References in periodicals archive ?
Hypertension was observed in 50% of children who received ACTH whereas only one developed cushingoid appearance.
Other minor side effects encountered were sleep disturbances, fatigue, bad taste and headache following initial few days of pulse, cushingoid features and weight gain, menstrual disturbance with polymenorrhagia in 2 females.
Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, nasopharyngitis.
Due to drugs and immunosuppression children develop infections, Cushingoid features, osteoporosis and anaemia.
In our series, approximately 50% of patients presented asymptomatically and had incidental findings, but symptom presentation from selected series can be highly variable ranging from Cushingoid features to simply constitutional symptoms.
No Cushingoid or other clinical symptoms were present.
In addition for transplantation patients receiving immunosuppression therapy, they may experience appearance changes including the Cushingoid facies and growth retardation related to long-term daily corticosteroid administration and the hirsutism and gingival hypertrophy [14].
Finger size was proportional and no prognathism, acromegaly, or Cushingoid features were appreciated.
However, there have been a few reported cases of metabolically active tumors secreting ACTH and catecholamines, causing hypertension and other cushingoid features in the affected patient [12, 13, 30].
The face shows signs of cushingoid features resulting from adverse side effects of corticosteroids.
A 15-year-old girl was admitted in November 2012 due to Cushingoid appearance for three years, the weight increase of 10 kg, and headache in the proceeding 1 year.
He gave one example of a patient who had been diagnosed with bullous pemphigoid several years before, and who was becoming Cushingoid as a result of steroids.