Cushing's syndrome

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Cushing syndrome

or Cushing's syndrome
n.
A group of symptoms, including a puffy face, fat accumulation around the torso, fat loss from legs and arms, and easy bruising, resulting from elevated levels of cortisol in the bloodstream that are caused either by excess production of the hormone ACTH, as from an adrenal or pituitary tumor, or by administration of high doses of corticosteroid hormones. Cushing syndrome caused by a pituitary tumor is called Cushing disease.

[After Harvey Williams Cushing.]

Cushing's syndrome

A condition caused by oversecretion of glucocorticoid hormones from the adrenals, resulting in a redistribution of body fat and other effects.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.Cushing's syndrome - a glandular disorder caused by excessive cortisol
adenosis, gland disease, glandular disease, glandular disorder - a disorder of the glands of the body
Translations

Cushing's syndrome

n. síndrome de Cushing, síndrome adrenogenital asociado con una producción excesiva de cortisol, caracterizado por obesidad y debilitamiento muscular.
References in periodicals archive ?
A 15-year-old girl was admitted in November 2012 due to Cushingoid appearance for three years, the weight increase of 10 kg, and headache in the proceeding 1 year.
He gave one example of a patient who had been diagnosed with bullous pemphigoid several years before, and who was becoming Cushingoid as a result of steroids.
A typical cushingoid body habitus is reached by adipose tissue deposition that characteristically results in moon facies, a buffalo hump, and truncal obesity.
Physically, she exhibited cushingoid appearance and complained of excessive weight gain and hair growth on the body.
14] Children with SAM who were admitted with one or a combination of clinical features such as coma, hypoglycaemia, hypothermia and bradycardia, had the worst survival probability compared with those who had other less SAM-related manifestations, such as herbal intoxication, Cushingoid facies, etc.
Nine (35%) patients developed side effects whilst on treatment; seven (27%) gained weight, four (15%) developed Cushingoid features and three (11%) developed steroid-induced diabetes.
Complications encountered in Group B were namely, Cushingoid appearance (n=12), GI upset (n=5), recurrence (n=6) and infection (n=3) (Fig.
His physical examination was unremarkable, and no cushingoid features, petechiae, or abdominal striae were detected.
Follow up after six months and six doses of cyclophoshamide, revealed cushingoid face, maintained oxygen saturation on room air and serum creatinine had improved to 1.
This is an important finding, as steroid toxicity is common and often leads to significant comorbidity such as Cushingoid features, weight gain, mood disorders, glucose intolerance, osteoporosis, and increased susceptibility to infection and cardiovascular disease.
In another case, an 11-year-old boy with iridocyclitis developed a cushingoid habitus and acanthosis nigricans after he was treated with prednisolone acetate 1% eye drops every 2 hours for 6 months (18).
Methods: The descriptive study was conducted at the Children's Hospital, Lahore, from April to September 2013, and comprised patients presenting with cushingoid features and history of using nappy rash ointments.