cyclic AMP


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Related to cyclic AMP: cyclic GMP, G protein

cyclic AMP

n. Abbr. cAMP
A cyclic nucleotide of adenosine that is produced inside cells in response to external stimuli, such as hormones, and triggers various biochemical pathways within the cell.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

cyclic AMP

n
(Biochemistry) cyclic adenosine monophosphate: a constituent of biological cells, responsible for triggering processes that are dependent on hormones
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

cyclic AMP


n.
a small molecule, a cyclic anhydride of AMP, that activates enzymes, amplifies the effects of hormones and neurotransmitters, and performs other vital functions within the cell.
[1965–70]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
References in periodicals archive ?
Cooper, "Differential distribution of exchange proteins directly activated by cyclic AMP within the adult rat retina," Neuroscience, vol.
Melatonin inhibits pituitary adenylyl cyclase-activating polypeptide-induced increase of cyclic AMP accumulation and [Ca2+] in cultured cells of neonatal rat pituitary.
Ogreid, "Arginine 210 is not a critical residue for the allosteric interactions mediated by binding of cyclic AMP to site a of regulatory (RI[alpha]) subunit of cyclic AMP-dependent protein kinase," Journal of Biological Chemistry, vol.
As vascular tone is finely regulated by cyclic nucleotides levels in the vascular smooth muscle, we have investigated the effect of BFBO on relaxations induced by agents elevating either cyclic GMP or cyclic AMP. BFBO at a concentration of 10 [micro]g/ml significantly potentiated the relaxation in response to cyclic GMP-elevating vasodilators such as atrial natriuretic peptide and SNP in rings without endothelium (Figs.
In contrast, CGRP inhibits bone resorption in vitro (Imai & Matsusue, 2002), and increases cyclic AMP (Bjurholm et al.) and intracellular calcium in osteoblasts (Kawase et al., 1995).
Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.
To address this limitation we estimated the ability of a FRET-based cyclic AMP (cAMP) sensor to detect changes in cAMP.
1,25-Dihydroxyvitamin D3 suppresses renin gene transcription by blocking the activity of the cyclic AMP response element in the renin gene promoter.
It is observed that most of the key metabolites are amino acids that are linked to cyclic AMP or cyclic dAMP, but glucose is also clearly correlated to several metabolites.
Palmer, "Regulating gene transcription in response to cyclic AMP elevation" Cellular Signalling, vol.
RESULTS: The EC expressed high levels of CRF and CRF2 receptors and bath application of CRF increased the frequency of picrotoxin-induced epileptiform activity recorded from layer III of the EC in slices, via CRF2 receptors and cyclic AMP, whereas protein kinase A was partially involved.
Parathyroid hormone induces protein kinase C but not adenylate cyclase in adult cardiomyocytes and regulates cyclic AMP levels via protein kinase C-dependent phosphodiesterase activity.

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