cyclic neutropenia


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Noun1.cyclic neutropenia - neutropenia that occurs periodically
neutropenia - leukopenia in which the decrease is primarily in number of neutrophils (the chief phagocytic leukocyte)
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References in periodicals archive ?
Since there was an abnormal number of neutrophils from birth, severe congenital neutropenia was considered primarily and acquired neutropenic cases and cyclic neutropenia were excluded.
In differential diagnosis, although there are periodic febrile illnesses such as cyclic neutropenia, familial mediterranean fever, Hyperimmunoglobulin D syndrome, the genetic basis of these diseases has been demonstrated and their findings are unique (10).
Cyclic neutropenia (CyN) is a rare stem cell disorder with a prevalence of one to two per million [1].
[2] In our patient, a differential diagnosis of (i) cyclic neutropenia, (ii) chronic congenital neutropenia, (iii) chronic idiopathic neutropenia and (iv) Schwachman-Diamond syndrome (exocrine pancreatic insufficiency with neutropenia) was considered.
Another view is that there may be underlying hypogammaglubulinemia, cyclic neutropenia or neutrophil dysfunction in healthy children who develop pseudomonas sepsis (1, 3, 7).
Among stereotypical recurrent fevers, irregular episodes likely indicate a monogenic fever syndrome, while more predictable episodes could be cyclic neutropenia or PFAPA.
She presented with PNDM and cyclic neutropenia at six-weeks of age.
More than 50% of patients with congenital severe neutropenia and nearly all patients with cyclic neutropenia harbour mutations in the ELANE gene encoding for the neutrophil elastase (NE), a broad-specificity serine protease localized in azurophil granules [82-84].