cyclophosphamide


Also found in: Medical, Acronyms, Encyclopedia, Wikipedia.
Related to cyclophosphamide: vincristine

cy·clo·phos·pha·mide

 (sī′klə-fŏs′fə-mīd′)
n.
A cytotoxic, immunosuppressive, antineoplastic drug, C7H15Cl2N2O2P, used in the treatment of Hodgkin and non-Hodgkin lymphomas and various other forms of cancer, including multiple myeloma, breast cancer, and certain types of leukemia.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

cyclophosphamide

(ˌsaɪkləʊˈfɒsfəˌmaɪd)
n
(Pharmacology) an alkylating agent used in the treatment of leukaemia and lymphomas
[C20: from cyclo- + phosph(orus) + amide]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
Translations

cy·clo·phos·pha·mide

n. ciclofosfamida, droga antineoplástica usada también como inmunosupresor en trasplantes.
English-Spanish Medical Dictionary © Farlex 2012

cyclophosphamide

n ciclofosfamida
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
The fetal weight has been reduced in those groups receiving cyclophosphamide associated to chlorophyllin and the values ranged from 1.14 [+ or -] 0.15 to 1.46 [+ or -] 0.11.
Other options to treat hemorrhagic cystitis are desirable and studies in experimental animals have shown that nonsteroidal anti-inflammatory agents, corticosteroids, or nitric oxide synthase inhibitors may exert protective effects on the urinary tract in cyclophosphamide or ifosfamide-induced cystitis [7-10].
However, fludarabine and cyclophosphamide can cause significant side effects such as severe blood complications and life-threatening infections, the researchers said.
The SCOT (Scleroderma: Cyclophosphamide or Transplantation) trial randomized 75 patients with severe scleroderma and substantial internal organ involvement to receive treatment with either cyclophosphamide or myeloablative radiation followed by immune reconstitution with an autologous hematopoietic stem cell transplant.
Out of all the patients who received immunosuppressive therapy, only two patients developed cytopenias requiring delay in dose of cyclophosphamide. None of the patients who received cyclophosphamide in our cohort developed hemorrhagic cystitis.
Drugs like doxorubicin, daunorubicin, docetaxel and cyclophosphamide are more likely to cause anagen effluvium.
Keywords: GIT, ADRs, Drugs, Cancer, Anticancer drugs, AC therapy Doxorubicin, Cyclophosphamide.
The initial treatment protocol for this patient's ALL included cyclophosphamide, which is metabolized to acrolein, a known urotoxin associated with hemorrhagic cystitis and bladder cancer.