The team, led by Dr Mushtaq Hussain of the Dow Research Institute of Biotechnology and Biomedical Sciences, replicated the genetic disorder cyclopia
in a fly from the Drosophila family, turning the insect into a mini model of the rare human abnormality.
The human brain and face: mechanisms of cranial, neurological and facial development revealed through malformations of holoprosencephaly, cyclopia
and aberrations in chromosome 18.
The calf, however, is suffering from a rare birth defect called cyclopia
, where the left and right hemispheres of the brain did not separate while in the womb.
Honey bush, a traditional South African shrub, Cyclopia
Many medicinal plants of African origin, such as Momordica charantia (bitter melon), Cyclopia
genistoides (honeybush), and Catharanthus roseus (Madagascan periwinkle), are effective against various diseases including diabetes mellitus .
Lee et al., "Cyclopia
and defective axial patterning in mice lacking sonic hedgehog gene function," Nature, vol.
Mashima, "HDlive rendering image of cyclopia
and a proboscis in a fetus with normal chromosomes at 32 weeks of gestation," Journal of Medical Ultrasonics, vol.
Several congenital ocular defects in pigs, such as anophthalmia, macro- and microphthalmia, and cyclopia
, have been documented in the veterinary literature .
Cyclops Goat A one-eyed goat was born in an Indian village with a deformity known as Cyclopia
. The animal has definitely become an attraction in Assam where it has surpassed all expectations and is still surviving in spite of the deformity.
The remaining but less frequently en countered anomalies were clubfoot deformity, cyclopia
, edema, flattened nose, hypotelorism, proboscis, sandal gap, and single uterine artery.
Gelderblom, "Effect of species variation and processing on phenolic composition and in vitro antioxidant activity of aqueous extracts of Cyclopia
Chae, "Protective effect of fermented Cyclopia
intermedia against UVB-induced damage in HaCaT human keratinocytes," BMC Complementary and Alternative Medicine, vol.