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 (sī′klə-spôr′ēn, -ĭn) also cy·clo·spor·in (-ĭn) or ci·clo·spor·in
An immunosuppressive drug obtained from the soil fungus Tolypocladium inflatum, used to prevent the rejection of transplanted organs.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˌsaɪkləʊˈspɔːrɪn) or


(Pharmacology) a variant spelling of ciclosporin
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
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Kogure, "Cyclosporin A protects against ischemia-reperfusion injury in the brain," Brain Research, vol.
Effects of plasma lipid levels on blood distribution and pharmacokinetics of cyclosporin A.
He was also given oral cyclosporin 25mg TDS and minocycline 100mg daily but without any significant response.
Cyclophilin inhibitors are cyclosporin, which has been around since 1971 after it was first isolated from the fungus Tolypocladium inflatum, or cyclosporin derivatives.
Patients with hepatotoxicity episodes had a high total mortality rate, higher incidence of positive pre-transplant cytomegalovirus (CMV) IgM test, higher creatinine values during the first month post-transplant, underwent additional acute rejection episodes, and received fewer cyclosporin A based ID.
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
Drugs including steroids, cyclophosphamide, cyclosporin, methotrexate, acyclovir, vincristine, and tacrolimus have been reported as causative agents in the etiology of posterior reversible encephalopathy syndrome (5).
They focused on the immunosuppressive drug cyclosporin A, which is widely used in the treatment of severe dry eye disease.
In the clinical trial, the team are now investigating how drug cyclosporin could limit heart damage after a heart attack by suppressing the activation of T-lymphocytes, stopping them from travelling into the heart muscle and damaging it.
Surgeons already use existing drugs such cyclosporin to achieve the same outcome exactly after a transplant, to stop the body rejecting a donated organ.
The present paper reports successful treatment of perianal fistula in dogs with cyclosporin and ketoconazole.