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 (sī′klə-spôr′ēn, -ĭn) also cy·clo·spor·in (-ĭn) or ci·clo·spor·in
An immunosuppressive drug obtained from the soil fungus Tolypocladium inflatum, used to prevent the rejection of transplanted organs.


(ˌsaɪ kləˈspɔr in, -ɪn, -ˈspoʊr-, ˌsɪk lə-)

also cy•clo•spo•rin


a product of certain soil fungi that suppresses immune reactions by disabling helper T cells, used esp. for minimizing rejection of transplants.
[1975–80; < New Latin Cyclospor(eae) a class of brown algae (see cyclo-, -spore) + -in1]


n. ciclosporina, agente inmunosupresivo usado en tranplantes de órganos.

cyclosporine, ciclosporin

(INN) n ciclosporina
References in periodicals archive ?
Cyclosporine and methotrexate appear to have the lowest risk of serious infection at 6 months for patients with atopic dermatitis (AD) receiving systemic therapy in a realworld setting, according to a recently published population-based study.
WEDNESDAY, July 17, 2019 (HealthDay News) -- In patients with membranous nephropathy at high risk for progressive disease, rituximab is noninferior to cyclosporine in inducing complete or partial remission of proteinuria at 12 months and is superior in maintaining proteinuria remission up to 24 months, according to a study published in the July 4 issue of the New England Journal of Medicine.
("China Medical System" or the "Company") announced that the Company introduced Tildrakizumab, a product used to treat psoriasis and psoriatic arthritis, and Cyclosporine A, 0.09% Eye Drops, a product used to treat dry eyes disease, from Sun Pharma, a leading Indian pharmaceutical company.
Cyclosporine, an immune modulatory drug is of proven use in diseases with underlying inflammation, such as psoriasis, rheumatoid arthritis, ulcerative colitis, as well as ocular inflammation.
Cyclosporine appears to be a good candidate as it inhibits T-cell inhibition which is an important component of ocular surface inflammation.
(Reuters: SUN.BO) (NSE: SUNPHARMA) (BSE: 524715) has received approval for Cequa (cyclosporine ophthalmic solution) 0.09%, from the US Food and Drug Administration, the company said.
It was reported yesterday that the United States Food and Drug Administration (USFDA) has granted approval to India-based Sun Pharmaceutical Industries for its dry eye disease treatment CEQUA (cyclosporine ophthalmic solution) 0.09%.
Herein we report a delayed diagnosis of Pyoderma gangrenosum of the penis resulting in partial damage and was effectively treated with cyclosporine.
"This study is unique in that it aims to not only capture more commonly employed interventions such as supportive care, surgical debridement, intravenous immunoglobulin [IVIG], and corticosteroids but also newer modalities that coincide with our improved understanding of the pathogenesis of the disease, such as the use of cyclosporine and biologies," said Mr.
In this study, we investigated the pharmacokinetics of the two tracers by in vivo PBPK modelling and studied the effects of transporter inhibition by cyclosporine on the pharmacokinetics of [[sup.11]C]MT107.
High-dose corticosteroids, cyclophosphamide, cyclosporine, intravenous (IV) immunoglobulins, and etoposide have been used for SLEassociated MAS [3-7].