cystic fibrosis


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cystic fibrosis

n. Abbr. CF
A genetic disease that involves dysfunction of the exocrine glands and affects many organs and organ systems, especially the respiratory system, the pancreas, the intestines, the sweat glands, and, in males, the reproductive system. It is characterized by the chronic accumulation of thick mucus in the lungs and pancreas, affecting breathing and digestion, and by recurring infections. Also called mucoviscidosis.

cystic fibrosis

n
(Pathology) an inheritable disease of the exocrine glands, controlled by a recessive gene: affected children inherit defective alleles from both parents. It is characterized by chronic infection of the respiratory tract and by pancreatic insufficiency

cys′tic fibro′sis


n.
a hereditary disease of the exocrine glands characterized by the production of thickened mucus that chronically clogs the bronchi and pancreatic ducts, leading to breathing difficulties, infection, and fibrosis.
[1950–55]

cys·tic fi·bro·sis

(sĭs′tĭk fī-brō′sĭs)
An inherited disease of certain glands, causing them to produce abnormally large amounts of thick mucus. It affects especially the pancreas and the mucus-secreting glands of the lungs, and results in problems with breathing and digestion.

cystic fibrosis

An inherited disease that involves oversecretion of a heavy mucus (thick, slimy fluid) that clogs the respiratory passages. Sufferers are more prone to catching fatal respiratory infections.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cystic fibrosis - the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
fibrosis - development of excess fibrous connective tissue in an organ
Translations

cystic fibrosis

cys·tic fi·bro·sis

[MIM*219700]
n. fibrosis cística del páncreas, fibroquiste.

cystic fibrosis

n fibrosis quística
References in periodicals archive ?
Professor Eshwar Mahenthiralingam, from Cardiff University's School of Biosciences, has studied cystic fibrosis lung infections for more than 20 years and is recognised as a leader in the study of problematic antibiotic resistant bacteria.
The specific defective gene that causes CF is the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
The Orlando Chapter of the Cystic Fibrosis Foundation held its 5th annual year of going vertical to cure cystic fibrosis on Saturday, September 27.
The average lung capacity for an adult with Cystic Fibrosis is just 65.
Researchers at the University of Missouri, Columbia, and the University of Iowa Iowa City, have taken the first step in developing a porcine cystic fibrosis model that may more closely mimic the disease in humans.
Elected vice president of Cystic Fibrosis Tasmania in 2002, Aaron became president last October.
The FDA and European Medicines Agency have both previously granted Bronchitol orphan drug status for treating cystic fibrosis.
A defective gene in the bodies of cystic fibrosis patients causes the body to produce abnormally thick, sticky mucus that clogs the lungs and leads to life-threatening infections.
1) In cystic fibrosis, abnormal sodium and chloride transport leads to obstruction and disease in the lungs, pancreas, paranasal sinuses, and sweat glands.
They then coated the wires with receptors harboring fragments of DNA that are complementary to the normal sequence of the gene implicated in cystic fibrosis.
As such, it delivers diverse protocols that cover topics ranging from the basic pathophysiology of cystic fibrosis to animal models and gene therapy.

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