cystic fibrosis


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cystic fibrosis

n. Abbr. CF
A genetic disease that involves dysfunction of the exocrine glands and affects many organs and organ systems, especially the respiratory system, the pancreas, the intestines, the sweat glands, and, in males, the reproductive system. It is characterized by the chronic accumulation of thick mucus in the lungs and pancreas, affecting breathing and digestion, and by recurring infections. Also called mucoviscidosis.

cystic fibrosis

n
(Pathology) an inheritable disease of the exocrine glands, controlled by a recessive gene: affected children inherit defective alleles from both parents. It is characterized by chronic infection of the respiratory tract and by pancreatic insufficiency

cys′tic fibro′sis


n.
a hereditary disease of the exocrine glands characterized by the production of thickened mucus that chronically clogs the bronchi and pancreatic ducts, leading to breathing difficulties, infection, and fibrosis.
[1950–55]

cys·tic fi·bro·sis

(sĭs′tĭk fī-brō′sĭs)
An inherited disease of certain glands, causing them to produce abnormally large amounts of thick mucus. It affects especially the pancreas and the mucus-secreting glands of the lungs, and results in problems with breathing and digestion.

cystic fibrosis

An inherited disease that involves oversecretion of a heavy mucus (thick, slimy fluid) that clogs the respiratory passages. Sufferers are more prone to catching fatal respiratory infections.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cystic fibrosis - the most common congenital disease; the child's lungs and intestines and pancreas become clogged with thick mucus; caused by defect in a single gene; no cure is known
monogenic disease, monogenic disorder - an inherited disease controlled by a single pair of genes
fibrosis - development of excess fibrous connective tissue in an organ
Translations

cystic fibrosis

cys·tic fi·bro·sis

[MIM*219700]
n. fibrosis cística del páncreas, fibroquiste.

cystic fibrosis

n fibrosis quística
References in periodicals archive ?
Goal set to raise $100K in support of the Cystic Fibrosis Foundation's mission.
Cystic fibrosis is a debilitating lifeshortening illness that creates a mucus build-up that causes chronic lung infections and progressive lung damage.
Release date- 09082019 - Biomedical scientists at KU Leuven and the University of Trento have used gene correction to fix two mutations that cause cystic fibrosis.
Biopharmaceutical company Aridis Pharmaceuticals Inc (Nasdaq:ARDS) reported on Wednesday that it has received the US Food and Drug Administration's (FDA) orphan drug designation (ODD) for the evaluation and development of AR-501 for treatment of lung infection in patients with cystic fibrosis.
Negotiations are currently ongoing between NHS England, NICE and Vertex so that cystic fibrosis patients could have access to Orkambi and Symkevi.
Orkambi is licensed to treat cystic fibrosis in patients from two-year-olds to adults, who have a specific genetic mutation known as F508del.
Michael Stephen, Drexel University College of Medicine Cystic Fibrosis center director.
Inclusion criteria were cystic fibrosis cases diagnosed by the department of pediatric pulmonary disease clinic and referred for dermatological evaluation and cases admitted to the dermatology department.
The 41-year-old, from Ryton, has spoken out as this week marks 1,000 days since the cystic fibrosis medicine Orkambi was licensed in the UK - but is still unavailable on the NHS.
The youngster, from Prestwich, has now written to Theresa May urging her to support a campaign to allow people with cystic fibrosis access to new medicines.
[ClickPress, Tue May 15 2018] "Cystic Fibrosis: Disease Insights and Market Forecasts to 2024" report delivers an in-depth understanding of the disease, historical & forecasted epidemiology of Cystic Fibrosis disease in the US, EU5 (Germany, France, Italy, Spain, UK), and Japan and the historical & forecasted market size, for Cystic Fibrosis, drug wise in $ sales and patient numbers at global level and in the US, EU5 (Germany, France, Italy, Spain, UK), Australia and Canada till 2024.
CAMPAIGNERS will hand over a petition to the Welsh Assembly on Wednesday calling for the "transformational" cystic fibrosis drug Orkambi to be made available in Wales.

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