cytochrome c


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Related to cytochrome c: Cytochrome c oxidase
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Noun1.cytochrome c - the most abundant and stable cytochrome; involved in energy transfer
cytochrome - (biochemistry) a class of hemoprotein whose principal biological function is electron transfer (especially in cellular respiration)
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References in periodicals archive ?
The present study was planned to investigate its molecular phylogeny and diversity analysisusing mitochondrial cytochrome b, cytochrome c and d-loop region.
The ETC consists of three proton pumps, NADH dehydrogenase (complex I), [bc.sub.1]-complex (complex III), and cytochrome c oxidase (COX; complex IV).
For instance, cytochrome c shuffles electrons around to help cells make energy.
The mitochondrial pathway is initiated by the release of apoptotic factors such as cytochrome c, apoptosis inducing factor (AIF) and endonuclease G from the mitochondrial intermembrane space by mitochondrial outer membrane permeabilization (MOMP), which is a complex process that involves numerous molecular players including Bcl-2 family (Brenner and Grimm, 2006; Kuwana and Newmeyer, 2003).
This event triggers the release of pro-apoptotic proteins, including cytochrome C, from the mitochondrial intermembrane space to the cytosol where they activate caspases and endonucleases that initiates apoptosis.
Two apoptotic pathways that converge on caspase-3, with one involving caspase-8 and the other involving the mitochondrial release of cytochrome c as well as the activation of caspase-9, have been described [6, 7].
It indicates that cytochrome C oxidase which plays an important role in generating ATP is a primary photoreceptor of light in the red to near-IR region of the spectrum [8-10].
The human cytochrome c oxidase is the terminal enzyme complex of the respiratory chain; it is located in the inner mitochondrial membrane where it catalyzes the transfer of electrons from reduced cytochrome c to molecular oxygen.
Reduced glutathione (GSH), 1-chloro-2,4-dinitrobenzene (CDNB), reduced nicotinamide adenine dinucleotide phosphate (NADPH), amidopyrine, cytochrome C, thiobarbituric acid and all other chemicals were purchased from Sigma Chemical Company (Saint Louis, USA).
Doxorubicin treatment in vivo causes cytochrome c releae and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency superoxide dismutase activity and Bcl-2: Bax Ratio 1.
Dose-dependently elevated mRNA and protein levels of Fas, and promoted apoptotic initiator caspase-8 (active form), a molecule of a death-receptor-dependent pathway, coupled with unaltered or decreased levels of cytosolic cytochrome c and the apoptotic initiator caspase-9 (active form), molecules of mitochondria-dependent pathways, may be indicative of cardiac apoptosis, which is Fas death-receptor apoptotic-signaling dependent, but not mitochondria pathway dependent in rats exposed to second-hand smoke (SHS).