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Related to cytokine: Cytokine storm


Any of various proteins, such as the interleukins and lymphokines, that are released by cells of the immune system and act in intercellular communication, especially in regulating inflammation and the immune response.

[cyto- + Greek kīnein, to move; see kinin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) any of various proteins, secreted by cells, that carry signals to neighbouring cells. Cytokines include interferon
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
protein - any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
TNF, tumor necrosis factor, tumour necrosis factor - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
lymphokine - a cytokine secreted by helper T cells in response to stimulation by antigens and that acts on other cells of the immune system (as by activating macrophages)
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
The preclinical data presented at this year's AACR annual meeting expand on previous findings for APVO436 showing its ability to demonstrate potent T-cell cytotoxicity of tumors expressing CD123 with reduced cytokine release, suggesting the potential for increased clinical benefit and an improved safety profile.
In order to maximize the explanatory power of the cytokine dataset in the three time-points and to identify correlated subgroups, a factor analysis was performed using the principal components method and Varimax rotation, reducing the number of variables according to the correlation or covariance patterns.
In spite of the anti-inflammatory effects of food restriction (FR), there is a lack of data demonstrating if the blood level of a specific cytokine could better express the beneficial anti-inflammatory effects of caloric restriction.
However, in adjunct therapy, we observed significant results (in terms of parasite clearance in visceral organs, increased pro-inflammatory cytokines response and decreased/ marginal increase of anti-inflammatory cytokine response).
M2 PHARMA-August 23, 2018-Nuevolution discloses identity of its 'Cytokine X' programme
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It has been postulated that Single Nucleotide Polymorphisms (SNPs) within coding and promoter sequences of cytokine genes could affect their secretion pattern (10,11).
Comparison of Plasma Cytokine Levels before and after Treatment with Rituximab in Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus-Associated Polyautoimmunity
Conclusion: The pro-inflammatory cytokine, tumour necrosis factor alpha, takes part in preparation of endometrial lining for implantation of embryo in assisted reproductive treatment procedures.
Cytokine hemoadsorption is found to be a safe and effective adjuvant in the management of sepsis.
Although several studies have been conducted to evaluate the cytokine response with regard to TH1/TH2 cell responses, very few have investigated the TH17 arm of T-cell response in patient populations [3].