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The internal framework of a eukaryotic cell, composed of protein filaments that provide structural support and drive the movement of the cell and its internal components, typically divided into three categories (microfilaments, intermediate filaments, and microtubules) based on the diameter and composition of the filaments.

cy′to·skel′e·tal (-ĭ-tl) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Biochemistry) a network of fibrous proteins that governs the shape and movement of a biological cell
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌsaɪ təˈskɛl ɪ tn)

a shifting lattice arrangement of structural and contractile components distributed throughout the cell cytoplasm, composed of microtubules, microfilaments, and larger filaments.
cy`to•skel′e•tal, adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytoskeleton - a microscopic network of actin filaments and microtubules in the cytoplasm of many living cells that gives the cell shape and coherence
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
cytol, cytoplasm - the protoplasm of a cell excluding the nucleus; is full of proteins that control cell metabolism
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
In summary, the cellular cytoskeleton network is involved in the SARS-CoV maturation and possibly replication process.
Specifically, the investigators examined the NK cell cytoskeleton (the part of each cell primarily responsible for the spatial organization of its components) during target cell killing in comparison to that of cytotoxic T cells.
In mammalian cells, Rho proteins Rho/Rac/Cdc42 regulate the formation of the actin cytoskeleton in stress fibers, lamellipodia, and filopodia (1).
It is of interest to note that both [beta]-actin and the precursor protein for bikunin, two proteins involved with the formation of the cytoskeleton, were both downregulated in fish treated with estrogenic chemicals.
It was also found that IGF or stretch does not change the organization of cells or the cell's cytoskeleton. This research is significant in that it shows a relationship between the chemical and mechanical stimuli within the heart.
Additional features of his model include cytoskeleton activity as a mechanism for "free will" to influence the synaptic connections of classical neuron "wiring," where the neurons magnify and transform the cytoskeletal action to influence other body organs.
"We focused on the embryonic cytoskeleton," he says.
The topics include the integration of cadherin adhesion and cytoskeleton at adherens junction, making connections: guidance cues and receptors at non-neural cell-cell-junctions, tuning collective cell migration by cell-cell junction regulation, beyond cell-cell adhesion: sensational cadherins for hearing and balance, and the loss of E-cadherin-dependent cell-cell adhesion and the development and progression of cancer.
Moreover, the dynamic cytoskeleton has been shown to play a vital role in mediating signaling pathways and regulating gene expression [20, 21].
The release is aided by the cell's inner structural proteins called the cytoskeleton, along with contracting protein machinery called actomyosin.
Aberrantly phosphorylated cytoskeletal proteins are associated with disrupted cytoskeleton, characteristic of neuronal damage in several human neurodegenerative diseases.