cytotoxic T cell


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cytotoxic T cell

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

killer T cell


n.
a killer cell that destroys target cells only when specifically activated by helper T cells.
Compare natural killer cell.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.cytotoxic T cell - T cell with CD8 receptor that recognizes antigens on the surface of a virus-infected cell and binds to the infected cell and kill it
T cell, T lymphocyte - a small lymphocyte developed in the thymus; it orchestrates the immune system's response to infected or malignant cells
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Contribution of virus-specific CD8+ cytotoxic T cell to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model.
The Wistar Institute of Anatomy and Biology (Philadelphia, PA) has patented a modified human cytotoxic T cell line, which is characterized by dual activity in vitro and in vivo against malignant cells and virus-infected cells, and effective and safe methods for use of the modified cells in adoptive therapy of cancer and untreatable vital diseases in MHCmismatched recipients, and in marrow purging to achieve complete eradication of residual tumor cells from marrows of patients with leukemia and other types of cancer.
The research team found that antigen-specific T-cell receptors in the human immune system may react with drugs, mistaking them for invading pathogens, and activate cytotoxic T cells, which produce proteins that attack the mistaken pathogens and bring collateral damage to healthy cells, leading to drug allergies.
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