One case report described a patient with acute promyelocytic leukemia who was treated with all-transretinoic acid, daunomycin
, cytarabine, and a short course of dexamethasone, and was diagnosed with AVN 2 years after the cessation of chemotherapy.
Sheil, "Observation of daunomycin
and nogalamycin complexes with duplex DNA using electrospray ionisation mass spectrometry," Rapid Communications in Mass Spectrometry, vol.
In the present study, an iminobiotinylated drug, iminobiotinylated daunomycin
(IDAU), was connected to avidin-immobilized magnetic nanoparticles (AMNPs) based on the avidin-iminobiotin binding system.
In the last two decades some 1,4-DHPs and structurally related compounds were discovered and approved as effective reversers of resistance to doxorubicin, daunomycin
, vinblastine, and vincristine, as other anticancer drugs [25, 38, 39].
Indeed, while all three MAPKs are activated following daunomycin
treatment and hypoxia/reoxygenation, only inhibition of ERK1/2 further potentiated cardiomyocyte apoptosis, suggesting a prosurvival role of the ERK1/2 kinases [65, 66].
(d) Anthracycline chemotherapeutic agents: doxorubicin and daunomycin
Inhibiting effect of the new cytotoxic antibiotic daunomycin
on nucleic acids and mitotic activity of HeLa cells.
(37) The hematologic agents implicated include cytosine arabinoside, vincristine, doxorubicin, methotrexate, cyclophosphamide, etoposide, daunomycin
, and prednisone; the agents for solid tumors include vinorelbine, docetaxel, paclitaxel, carboplatin, cisplatin, gemcitabine, and 5-fluorouracil.
as an inhibitor of human lens epithelial cell proliferation in culture.
Corticosteroids [1-6] antiproliferative agents (5-fluorouracil and other fluoropyrimidines, taxol, doxorubicin, mycophenolate mofetil..., alone or in combination or with different delivery systems) [3-12], systemic, periocular, intraocular steroidal, and nonsteroidal anti-inflammatory agents [5,13-16], colchicine , daunomycin
, tissue plasminogen activator , heparin [12,18-20], interferon-gamma [21,22], calcium channel blockers , prolyl and lysyl hydroxylase inhibitors [19,24-26], retinoic acid [27,28], alpha-tocopherol [29-31], disintegrins , siRNA-PKCa ...
Two anthracyclines, daunomycin
(daunorubicin) and doxorubicin hydrochloride (hydroxyl daunomycin
or doxorubicin), were initially isolated from Streptomyces peucetius var.
Hamilton, "Stereochemistry of intercalation: interaction of daunomycin
with DNA," Nature: New Biology, vol.